Featured Research

from universities, journals, and other organizations

Obesity may increase risk of Clostridium difficile infection

Date:
October 24, 2013
Source:
Boston University Medical Center
Summary:
Researchers have identified obesity as a possible risk factor for Clostridium difficile infection. These findings may contribute to improved clinical surveillance of those at highest risk of disease.

Researchers from Boston Medical Center (BMC) and Boston University School of Medicine (BUSM) have identified obesity as a possible risk factor for clostridium difficile infection (CDI). These findings, which appear online in Emerging Infectious Diseases, may contribute to improved clinical surveillance of those at highest risk of disease.

CDI is a bacterial infection of the gut which has traditionally been described as a healthcare associated infection. CDIs have a profound economic impact on the healthcare system with estimated costs ranging from $496 million to more than $1 billion and are leading cause of infectious diarrhea in hospitalized patients.

During the past decade, the annual number of hospital discharge diagnoses of CDI have doubled from approximately 139,000 to 336,600 and physicians are starting to see these infections in traditionally low risk patients without any healthcare or antibiotic exposure. According to the researchers this has raised the concern for whether there are yet unidentified risk factors increasing the probability of CDI in a subset of individuals.

The researchers examined three groups of patients with CDI--those who were admitted from the community with no risk factors, those who had prior exposure to hospitals or clinics, and those who had onset of disease in the hospital. "We hypothesized that in a group without healthcare exposure, the significance of other risk factors would be increased. In particular, we were interested in inflammatory bowel disease which has previously been associated with higher risk of acquiring this infection and obesity, which has never been examined," explained corresponding author Nahid Bhadelia, MD, MALD, associate hospital epidemiologist at BMC and assistant professor of medicine at BUSM.

The researchers found that cases with community onset infection were four times more likely to be obese compared to those who had prior known exposure to a healthcare facility. These patients were also five times more likely to have inflammatory bowel disease (IBD). "We were also surprised to note that our patients who were presenting from the community were almost twice as likely to be obese as the general population in Massachusetts (34 percent compared to 23 percent). Hence, like IBD, obesity may be associated with higher risk of CDI," added Bhadelia.


Story Source:

The above story is based on materials provided by Boston University Medical Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. Florence Fenollar, MD, PhD; Marie Cιlard, MD; Jean-Christophe Lagier, MD; Hubert Lepidi, MD, PhD; Pierre-Edouard Fournier, MD, PhD; and Didier Raoult, MD, PhD,. Possible Association between Obesity and Clostridium difficile Infection. Emerging Infectious Diseases, October 2013

Cite This Page:

Boston University Medical Center. "Obesity may increase risk of Clostridium difficile infection." ScienceDaily. ScienceDaily, 24 October 2013. <www.sciencedaily.com/releases/2013/10/131024121758.htm>.
Boston University Medical Center. (2013, October 24). Obesity may increase risk of Clostridium difficile infection. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2013/10/131024121758.htm
Boston University Medical Center. "Obesity may increase risk of Clostridium difficile infection." ScienceDaily. www.sciencedaily.com/releases/2013/10/131024121758.htm (accessed April 18, 2014).

Share This



More Health & Medicine News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) — The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) — President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com
Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) — A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) — A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins