Featured Research

from universities, journals, and other organizations

Fight or flight and the evolution of pain

Date:
January 7, 2014
Source:
Molecular Biology and Evolution (Oxford University Press)
Summary:
Hard wired into the survival mechanisms of all animals is the perception of pain. Different stimuli, such as heat or cold, foul odors, chemicals or a blunt blow can trigger pain receptors in the body that, in the blink of an eye, jolt the body into classic fight or flight responses. Researcher Shigeru Saito, et. al. have performed the first evolutionary analysis of pain response in chickens by isolating the genes for pain receptors called TRPA1.

Hard wired into the survival mechanisms of all animals is the perception of pain. Different stimuli, such as heat or cold, foul odors, chemicals or a blunt blow can trigger pain receptors in the body that, in the blink of an eye, jolt the body into classic fight or flight responses.

Related Articles


Researcher Shigeru Saito, et. al. have performed the first evolutionary analysis of pain response in chickens by isolating the genes for pain receptors called TRPA1. They were able to examine the function of the receptor using different stimuli and in comparison with other vertebrate species. They found that heat stimulation activated chicken TRPA1, sharing similar thermal properties with other cold blood animals such as frog and reptile TRPA1 rather than mammalian and human TRPA1.

In addition, they identified for the first time in chickens that methyl anthranilate (MA), a repellent chemical for birds, also activates chicken TRPA1. MA-induced activity of TRPA1 varied among diverse vertebrate species and three key amino acid residues involved in the TRPA1 activity by MA were identified. The findings add to the understanding of the functional evolution of TRPA1 and its sensitivity to heat as well as its diversification among vertebrate species.


Story Source:

The above story is based on materials provided by Molecular Biology and Evolution (Oxford University Press). Note: Materials may be edited for content and length.


Journal Reference:

  1. S. Saito, N. Banzawa, N. Fukuta, C. T. Saito, K. Takahashi, T. Imagawa, T. Ohta, M. Tominaga. Heat and noxious chemical sensor, chicken TRPA1, as a target of bird repellents and identification of its structural determinants by multispecies functional comparison. Molecular Biology and Evolution, 2014; DOI: 10.1093/molbev/msu001

Cite This Page:

Molecular Biology and Evolution (Oxford University Press). "Fight or flight and the evolution of pain." ScienceDaily. ScienceDaily, 7 January 2014. <www.sciencedaily.com/releases/2014/01/140107215355.htm>.
Molecular Biology and Evolution (Oxford University Press). (2014, January 7). Fight or flight and the evolution of pain. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/2014/01/140107215355.htm
Molecular Biology and Evolution (Oxford University Press). "Fight or flight and the evolution of pain." ScienceDaily. www.sciencedaily.com/releases/2014/01/140107215355.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Plants & Animals News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Bionic Ants Could Be Tomorrow's Factory Workers

Bionic Ants Could Be Tomorrow's Factory Workers

Reuters - Innovations Video Online (Mar. 30, 2015) Industrious 3D printed bionic ants working together could toil in the factories of the future, says German technology company Festo. The robotic insects cooperate and coordinate their actions and movements to achieve a common aim. Amy Pollock reports. Video provided by Reuters
Powered by NewsLook.com
Captive-Born Panda Triplets Are Eight Months Old

Captive-Born Panda Triplets Are Eight Months Old

Reuters - Light News Video Online (Mar. 30, 2015) The world&apos;s only surviving captivity-born panda triplets turn eight months old, according to China’s state media. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Lions Make Surprise Comeback in Gabon

Lions Make Surprise Comeback in Gabon

AFP (Mar. 30, 2015) Lions have made a comeback in southeast Gabon, after disappearing for years, according to live footage from US wildlife organisation Panthera. Duration: 00:32 Video provided by AFP
Powered by NewsLook.com
Ancient Egyptian Beer Making Vessels Discovered in Israel

Ancient Egyptian Beer Making Vessels Discovered in Israel

AFP (Mar. 30, 2015) Fragments of pottery used by Egyptians to make beer and dating back 5,000 years have been discovered on a building site in Tel Aviv, the Israeli Antiquities Authority said on Sunday. Duration: 00:51 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins