WEST LAFAYETTE, Ind. - African-American and Caucasian adolescent girls handle sodium and calcium differently, which may help explain why the races have different rates of hypertension and osteoporosis, according to research at Purdue University.
In a study published in the April edition of the American Journal of Clinical Nutrition, nutrition researchers discovered Caucasian girls lose more calcium in their urine than African-American girls, but both races lose calcium at an accelerated rate when they consume a high-salt diet.
"While we found a racial difference in calcium retention in adolescents, we also confirmed that blacks retain more sodium on a high-salt diet than whites," said Connie Weaver, distinguished professor and head of Purdue's Department of Foods and Nutrition. "This proves that salt is processed differently in the races, but too much salt in the diet reduces bone density in both races."
One out of four Caucasians will be diagnosed with osteoporosis, a bone-loss disease that costs Americans $14 billion a year in health care. The disease strikes one out of 10 African-Americans, but studies show they are more susceptible to hypertension, Weaver said.
"Sodium causes water retention, which leads to high blood pressure, and that could be related to the high prevalence of hypertension in adult blacks," Weaver said. "So even though salt intake is less critical to blacks with respect to building bones, we still have to be concerned about how sodium affects heart health."
The research results were based on figures from Purdue's Camp Calcium. The summer camp, funded by the National Institutes of Health since 1990, is designed to investigate various aspects of calcium metabolism in adolescent girls and boys.
Thirty-five campers were selected to participate in two, 20-day summer camps separated by two weeks. While housed on campus, the girls ate a controlled diet that provided certain amounts of calcium and other nutrients under 24-hour supervision.
The camp participants included 22 African-American girls and 13 Caucasian girls between the ages of 10 and 15. Berdine Martin, research associate and Camp Calcium project director, said the age range was important because, as an earlier Camp Calcium study found, calcium absorption is highest just after a girl's first menstrual cycle.
"Hormones affect the way the body retains calcium," Martin said. "Almost 40 percent of adult peak bone mass is acquired during adolescence, so we can directly affect the way a body ages by regulating calcium at this age."
During the first session, half of the girls received a low-sodium diet and half received a high-sodium diet. The diet was reversed during the second session.
"Salt intake affects how the body uses calcium at a critical time of bone development in young girls, but in whites more than in blacks," Weaver said. "This is something that should be easy to monitor in order not only to ensure healthy bones in adults, but also to reduce health-care costs of our aging populations."
Weaver says the strength of this research is the fact that the diets were strictly controlled and monitored in a clinical setting. While a longer study would reveal even more information, it would be difficult to control a diet as tightly as is possible at Camp Calcium, she said.
Research will continue to examine racial differences in how bodies handle calcium during this year's camp, when the focus will be on Asian adolescents. Girls between 12 and 14 and boys between 13 and 15 will attend the six-week camp in two three-week periods and participate in science classes, arts and crafts, sports, nutrition classes, and field trips, all while their diets are under strict supervision for calcium. For more information and an application packet, contact Berdine Martin, 700 W. State St., Purdue University, West Lafayette, Ind. 47907-2059 or call (800) 830-0175 or (765) 494-6559.
Weaver is an internationally recognized expert on calcium metabolism and bone health. She was a member of the Dietary Guidelines Advisory Committee, which gave recommendations to the U.S. Department of Agriculture to produce the most recent "Dietary Guidelines for Americans." She is director of the National Institutes of Health Botanicals Research Center for Age Related Diseases and past president of the American Society for Nutritional Sciences.
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