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Largest ever dataset of individual deaths in Africa, SE Asia reveals changing health

Date:
October 29, 2014
Source:
Wellcome Trust
Summary:
An unprecedented insight into the changing health of people across Africa and Asia -- including the fluctuating burdens of HIV, malaria and childhood mortality -- is revealed today by the publication of the largest ever dataset of individual deaths recorded on-the-ground.
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More than 110,000 individual deaths and their causes across 13 countries (including Ghana, South Africa, Kenya, Bangladesh and Vietnam) are contained in the new INDEPTH dataset. The data, collected by hundreds of researchers over two decades, are the first meaningful community-based information about cause of death in countries where individual deaths are not recorded automatically by national governments.

The INDEPTH cause of death findings are published in a special issue of the journal Global Health Action, which is fully open access. There are six multisite papers dealing with specific causes of death: HIV/AIDS, malaria, pregnancy-related factors, external causes (including accidental death and suicide), adult non-communicable diseases and childhood illness. Other papers describe methods, and many sites have contributed papers with local details. The project has been substantially funded by the Wellcome Trust.

The data were collected in 22 sites, each containing around 100,000 people. Each death was recorded by a researcher in the field who conducted a standardised verbal autopsy, a structured interview with a family member of the deceased. Data were processed by computer to establish likely causes of death.

The entire dataset (which is also available in the public domain) includes cause-of-death data collected as far back as 1992 for some sites, and it represents more than a century of working time. It also proves that data relating to cause of death can be reliably collected by non-medical staff outside of a clinical setting.

Overall, the data provide a strong case for the value of recording cause of death for planning and improving public health services. They show high variability in cause of death across sites, particularly in deaths caused by endemic diseases such as malaria and HIV. Although the picture is complex, there is some evidence to link mortality with differing investment in healthcare over the two decades of the study. For example, an INDEPTH site in rural northeast South Africa has documented the peak of HIV/AIDS-related deaths and is now seeing a substantial decline in HIV/AIDS mortality as public health programmes start to take effect.

The INDEPTH collaboration is able to estimate the global burden of major diseases. For example, they calculate that that under-five child mortality ranged from 15 per 1,000 in the Vietnamese site to 152 per 1,000 in one Kenyan site. Malaria mortality ranged from zero at one Bangladeshi site to more than 2 per 1,000 in parts of Africa. The level of HIV/AIDS mortality was more than 300 times higher in some African sites than it was in Asia.

Unlike other mortality estimates (e.g. the ones made by United Nations agencies and the Global Burden of Disease project in Seattle), which are based on mathematical models, the INDEPTH estimates are based on information about real deaths in defined areas of the population. Encouragingly for researchers, the findings of INDEPTH are very similar to the outputs from the mathematical modelling techniques, indicating that they confirm each other.

There are other important specific findings from the dataset. Across the countries, the data show consistently high rates of maternal and childhood mortality. Childhood drowning in Bangladesh and homicide among adult males in eastern and southern Africa are other causes for concern. Mortality from non-communicable diseases, particularly in younger adulthood, is an emerging problem that accounts for a high proportion of deaths in Asian countries.

Osman Sankoh, Executive Director of INDEPTH, said: "It pleases me to note that our own scientists have conducted the research, generated, cleaned and analysed the data, and have written the papers in this journal. Together with these publications we are making the datasets freely and widely accessible to the public on the INDEPTH Data Repository. This INDEPTH approach confirms that if scientists from low- and middle-income countries are funded to be able to analyse their data and publish their work, they will unquestionably make their data publicly available."

Peter Byass, Director of the Umeå Centre for Global Health Research in Sweden and a long-term member of the INDEPTH collaboration, said: "Good cause-of-death data are absolutely essential to well-functioning public health systems. Thinly stretched healthcare providers are not necessarily best-placed to consistently deliver reliable cause-of-death data, and many deaths do not occur in health facilities."

He added: "We have shown here that standardised verbal autopsies -- now typically reduced to a 15-minute interview with a family member and carried out by non-clinical staff -- can provide valuable data at modest cost and effort."

Jimmy Whitworth, Head of Population Health at the Wellcome Trust, said: "This unprecedented release of population-based cause-of-death information from sites across Africa and Asia gives us an invaluable insight into patterns of mortality across low- and middle-income countries. This information and the underlying datasets, which are openly accessible, will be immensely useful to researchers, policy makers and planners. This shows what can be achieved by bringing together sentinel sites collecting health information into a common network."

Ties Boerma, Director of Health Statistics and Information Systems at the World Health Organization, who has written an accompanying editorial for the special issue of Global Health Action, said that INDEPTH "presents the largest dataset of this nature ever," adding that this work "needs to be considered in the context of the need to strengthen country civil registration and vital statistics systems, and should be a central element in the post-2015 development agenda."

The special issue of Global Health Action is available at: http://www.globalhealthaction.net/index.php/gha/issue/view/1602#INDEPTH%20Network%20Cause-Specific%20Mortality


Story Source:

Materials provided by Wellcome Trust. Note: Content may be edited for style and length.


Journal References:

  1. Ties Boerma. Moving towards better cause of death registration in Africa and Asia. Global Health Action, October 2014 DOI: 10.3402/gha.v7.25931
  2. P. Kim Streatfield, Wasif A. Khan, Abbas Bhuiya, Nurul Alam, Ali Sié, Abdramane B. Soura, Bassirou Bonfoh, Eliezer K. Ngoran, Berhe Weldearegawi, Momodou Jasseh, Abraham Oduro, Margaret Gyapong, Shashi Kant, Sanjay Juvekar, Siswanto Wilopo, Thomas N. Williams, Frank O. Odhiambo, Donatien Beguy, Alex Ezeh, Catherine Kyobutungi, Amelia Crampin, Valérie Delaunay, Stephen M. Tollman, Kobus Herbst, Nguyen T.K. Chuc, Osman A. Sankoh, Marcel Tanner, Peter Byass. Cause-specific mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites. Global Health Action, October 2014 DOI: 10.3402/gha.v7.25362

Cite This Page:

Wellcome Trust. "Largest ever dataset of individual deaths in Africa, SE Asia reveals changing health." ScienceDaily. ScienceDaily, 29 October 2014. <www.sciencedaily.com/releases/2014/10/141029124504.htm>.
Wellcome Trust. (2014, October 29). Largest ever dataset of individual deaths in Africa, SE Asia reveals changing health. ScienceDaily. Retrieved October 13, 2024 from www.sciencedaily.com/releases/2014/10/141029124504.htm
Wellcome Trust. "Largest ever dataset of individual deaths in Africa, SE Asia reveals changing health." ScienceDaily. www.sciencedaily.com/releases/2014/10/141029124504.htm (accessed October 13, 2024).

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