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Vitamin D supplementation not associated with lower blood pressure, review suggests

Date:
March 16, 2015
Source:
The JAMA Network Journals
Summary:
A review of clinical trial data suggests vitamin D supplementation was ineffective at lowering blood pressure and should not be used as an antihypertensive, according to an article.
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A review of clinical trial data suggests vitamin D supplementation was ineffective at lowering blood pressure (BP) and should not be used as an antihypertensive, according to an article published online by JAMA Internal Medicine.

Intervention studies have produced conflicting evidence on the BP-lowering effect of vitamin D. An increasing number of clinical trials of have studied vitamin D and cardiovascular health, according to the study background.

Miles D. Witham, B.M., B.Ch., Ph.D., of the University of Dundee, Scotland, and coauthors analyzed clinical trial data and individual patient data with regard to vitamin D supplementation and BP. The authors included 46 trials (4,541 participants) and individual patient data were obtained for 27 trials (3,092 participants).

In both clinical trial and individual patient data, no effect was seen on systolic BP or diastolic BP due to vitamin D supplementation

"The results of this analysis do not support the use of vitamin D or its analogues as an individual patient treatment for hypertension or as a population-level intervention to lower BP," the study concludes.


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Materials provided by The JAMA Network Journals. Note: Content may be edited for style and length.


Journal Reference:

  1. Louise A. Beveridge, Allan D. Struthers, Faisel Khan, Rolf Jorde, Robert Scragg, Helen M. Macdonald, Jessica A. Alvarez, Rebecca S. Boxer, Andrea Dalbeni, Adam D. Gepner, Nicole M. Isbel, Thomas Larsen, Jitender Nagpal, William G. Petchey, Hans Stricker, Franziska Strobel, Vin Tangpricha, Laura Toxqui, M. Pilar Vaquero, Louise Wamberg, Armin Zittermann, Miles D. Witham. Effect of Vitamin D Supplementation on Blood Pressure. JAMA Internal Medicine, 2015; DOI: 10.1001/jamainternmed.2015.0237

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The JAMA Network Journals. "Vitamin D supplementation not associated with lower blood pressure, review suggests." ScienceDaily. ScienceDaily, 16 March 2015. <www.sciencedaily.com/releases/2015/03/150316121927.htm>.
The JAMA Network Journals. (2015, March 16). Vitamin D supplementation not associated with lower blood pressure, review suggests. ScienceDaily. Retrieved May 23, 2017 from www.sciencedaily.com/releases/2015/03/150316121927.htm
The JAMA Network Journals. "Vitamin D supplementation not associated with lower blood pressure, review suggests." ScienceDaily. www.sciencedaily.com/releases/2015/03/150316121927.htm (accessed May 23, 2017).

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