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Bid for bandages to enter the electronic age: Electrical stimulation promotes healing

Date:
May 14, 2015
Source:
University of Manchester
Summary:
The most detailed study to date showing how electrical stimulation accelerates wound healing has now been carried out.
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Skin wounds that are slow to heal are a clinical challenge to physicians all over the world. Every year, the NHS alone spends £1 billion on treating chronic wounds such as lower limb venous and diabetic ulcers. Wounds become chronic when they fail to heal and remain open for longer than six weeks.

Researchers from The University of Manchester carried out the unique human volunteer study of skin wound healing in 40 individuals with the results published in the journal PLOS ONE.

This study has provided new data supporting previous work by the team, enabling a new partnership with Oxford BioElectronics Ltd, which in collaboration with the University, will develop and evaluate devices and dressings for faster healing of wounds.

In the new research, half-centimetre, harmless wounds were created on each upper arm of the volunteers. One wound was left to heal normally while the other was treated with electrical pulses over a period of two weeks. These pulses stimulated the process through which new blood vessels form -- known as angiogenesis -- increasing the blood flow to the damaged area and resulting in the wounds healing significantly faster.

Now, the researchers at the University's Institute of Inflammation and Repair led by Dr Ardeshir Bayat are to work with Oxford BioElectronics Ltd on a five-year project to develop and evaluate devices and dressings which use the same techniques to stimulate the body's nervous system to generate nerve impulses to the site of skin repair.

Dr Ardeshir Bayat, the principal investigator from the University, is also leading on the partnership. He said: "This research has shown the effectiveness of electrical stimulation in wound healing, and therefore we believe this technology has the potential to be applied to any situation where faster wound healing is particularly desirable, such as following human or veterinary surgical wounds, accidental, or military trauma and in sports injuries."

Dr Bayat, an international expert in the subject of wound healing added: "This is an exciting partnership, working on a pioneering project with the potential to change substantially the way cutaneous wounds are managed in the future."

Dr Bayat concluded: "When used in acute and chronic wounds, bandages are essentially just a covering. With this technology we hope that the dressings will be able to make a significant functional contribution to healing the wounds and getting the patient back to full health as quickly as possible."


Story Source:

Materials provided by University of Manchester. Note: Content may be edited for style and length.


Journal Reference:

  1. Sara Ud-Din, Anil Sebastian, Pamela Giddings, James Colthurst, Sigrid Whiteside, Julie Morris, Richard Nuccitelli, Christine Pullar, Mo Baguneid, Ardeshir Bayat. Angiogenesis Is Induced and Wound Size Is Reduced by Electrical Stimulation in an Acute Wound Healing Model in Human Skin. PLOS ONE, 2015; 10 (4): e0124502 DOI: 10.1371/journal.pone.0124502

Cite This Page:

University of Manchester. "Bid for bandages to enter the electronic age: Electrical stimulation promotes healing." ScienceDaily. ScienceDaily, 14 May 2015. <www.sciencedaily.com/releases/2015/05/150514095243.htm>.
University of Manchester. (2015, May 14). Bid for bandages to enter the electronic age: Electrical stimulation promotes healing. ScienceDaily. Retrieved April 19, 2024 from www.sciencedaily.com/releases/2015/05/150514095243.htm
University of Manchester. "Bid for bandages to enter the electronic age: Electrical stimulation promotes healing." ScienceDaily. www.sciencedaily.com/releases/2015/05/150514095243.htm (accessed April 19, 2024).

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