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Low levels of hormone in African-Americans may increase hypertension

Date:
June 10, 2015
Source:
American College of Cardiology
Summary:
Although hypertension is more common in African-Americans, they have significantly lower levels of a hormone produced in response to cardiac stress than white and Hispanic individuals, a finding that may indicate a target for prevention or treatment of heart disease, according to a study.
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Although hypertension is more common in African-Americans, they have significantly lower levels of a hormone produced in response to cardiac stress than white and Hispanic individuals, a finding that may indicate a target for prevention or treatment of heart disease, according to a study published in JACC: Heart Failure.

Using data from the Dallas Heart Study, researchers assessed 3,148 patients and examined the association between race and ethnicity and levels of natriuretic peptides -- which are hormones produced in response to increased cardiac wall stress common in conditions like hypertension and heart failure.

African-Americans made up 51 percent of the study population and had the highest prevalence of hypertension at 41 percent. Despite the higher rate of hypertension among African-Americans, low natriuretic peptide levels were found more than twice as often compared to White individuals.

Researchers suggest that some African-American individuals may have a relative natriuretic peptide deficiency that predisposes to salt retention, hypertension, and cardiovascular risk. Consequently, natriuretic peptide deficiency may represent a target for prevention and treatment of heart disease.


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Materials provided by American College of Cardiology. Note: Content may be edited for style and length.


Journal Reference:

  1. Thomas J. Wang, MD et al. Racial Differences in Natriuretic Peptide Levels: The Dallas Heart Study. JACC: Heart Failure, June 2015 DOI: 10.1016/j.jchf.2015.02.008

Cite This Page:

American College of Cardiology. "Low levels of hormone in African-Americans may increase hypertension." ScienceDaily. ScienceDaily, 10 June 2015. <www.sciencedaily.com/releases/2015/06/150610152214.htm>.
American College of Cardiology. (2015, June 10). Low levels of hormone in African-Americans may increase hypertension. ScienceDaily. Retrieved May 23, 2017 from www.sciencedaily.com/releases/2015/06/150610152214.htm
American College of Cardiology. "Low levels of hormone in African-Americans may increase hypertension." ScienceDaily. www.sciencedaily.com/releases/2015/06/150610152214.htm (accessed May 23, 2017).

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