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Surgery improves quality of life for patients with chronic sinus infection, sleep dysfunction

Date:
September 10, 2015
Source:
The JAMA Network Journals
Summary:
Patients with chronic rhinosinusitis (sinus infection) and obstructive sleep apnea report a poor quality of life, which is substantially improved following endoscopic sinus surgery, according to a study.
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Patients with chronic rhinosinusitis (sinus infection) and obstructive sleep apnea report a poor quality of life, which is substantially improved following endoscopic sinus surgery, according to a study published online by JAMA Otolaryngology-Head & Neck Surgery.

A growing body of literature has highlighted the important links between quality of life (QOL), sleep, and chronic rhinosinusitis (CRS), such that disease severity has been correlated with worse QOL and patients with worse QOL have poor sleep. It is possible that CRS propagates sleep dysfunction through many cofactors including nightly wakening, nasal obstruction, depression and pain, according to background information in the article.

Timothy L. Smith, M.D., M.P.H., of Oregon Health & Science University, Portland, and colleagues investigated the impact of comorbid obstructive sleep apnea (OSA) on CRS disease-specific QOL and sleep dysfunction in patients with CRS following functional endoscopic sinus surgery (FESS). The study included 405 patients with a diagnosis of CRS who underwent FESS. Of these participants, 60 (15 percent) had comorbid OSA. A [total of 285 (70 percent) participants provided preoperative and postoperative survey responses for various measures, with an average of 13.7 months of follow-up.

There was no difference found between those with and without OSA in regards to disease severity or CRS disease-specific QOL, poor sleep, or average sleep quality scores prior to surgery. Following FESS, substantial gains in QOL and disease severity were observed for patients with CRS with and without OSA, and these gains were statistically significant. Participants without OSA reported greater improvements on sleep quality.

"Patients with OSA should be treated concurrently for both CRS and OSA to optimize sleep dysfunction and QOL improvement. Future investigations are needed to further elucidate the discordance and underlying mechanisms of sleep improvement between those patients with and without OSA with objective sleep measures," the authors write.


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Materials provided by The JAMA Network Journals. Note: Content may be edited for style and length.


Journal Reference:

  1. Timothy L. Smith, M.D., M.P.H et al. Quality of Life in Patients With Chronic Rhinosinusitis and Sleep Dysfunction Undergoing Endoscopic Sinus Surgery: A Pilot Investigation of Comorbid Obstructive Sleep Apnea. JAMA Otolaryngol Head Neck Surg, September 2015 DOI: 10.1001/.jamaoto.2015.1673

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The JAMA Network Journals. "Surgery improves quality of life for patients with chronic sinus infection, sleep dysfunction." ScienceDaily. ScienceDaily, 10 September 2015. <www.sciencedaily.com/releases/2015/09/150910131756.htm>.
The JAMA Network Journals. (2015, September 10). Surgery improves quality of life for patients with chronic sinus infection, sleep dysfunction. ScienceDaily. Retrieved May 28, 2017 from www.sciencedaily.com/releases/2015/09/150910131756.htm
The JAMA Network Journals. "Surgery improves quality of life for patients with chronic sinus infection, sleep dysfunction." ScienceDaily. www.sciencedaily.com/releases/2015/09/150910131756.htm (accessed May 28, 2017).

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