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Researchers study differences in ischemic stroke in marijuana users

Stroke in marijuana users more often caused by narrowing of arteries in skull

Date:
October 26, 2015
Source:
American College of Cardiology
Summary:
Strokes in young adults who use marijuana are more likely to be caused by stenosis, narrowing of the arteries, in the skull than strokes in non-users, new research shows. Previous studies found an association between marijuana use and stroke, but the new study is the first to explore differences in stroke in marijuana users and non-users, an approach that can help identify possible mechanisms for stroke in users.
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A new study found strokes in young adults who use marijuana are more likely to be caused by stenosis, narrowing of the arteries, in the skull than strokes in non-users.

Previous studies have found an association between marijuana use and stroke, but the new study published as a research letter in the Nov. 3 issue of the Journal of the American College of Cardiology is the first to explore differences in stroke in marijuana users and non-users, an approach that can help researchers begin to identify possible mechanisms for stroke in users.

The researchers from The University Hospital of Strasbourg in Strasbourg, France, looked at all patients under age 45 admitted with ischemic stroke from 2005 to 2014, creating a study cohort of 334 patients, including 58 who were marijuana users. Ischemic stroke is caused by a blockage that interrupts or reduces blood flow to the brain as opposed to hemorrhagic stroke, which occurs when a blood vessel in the brain leaks or ruptures.

In marijuana users in the study, ischemic stroke was more likely to be caused by intracranial arterial stenosis, a condition where there is narrowing the arteries inside the skull caused by a buildup of plaque. Intracranial arterial stenosis was found in 45 percent of the marijuana users in the study compared to 14 percent of the non-users.

Marijuana users in the study were younger, more likely to be male, more likely to smoke tobacco, and more likely to have other lifestyle risk factors than non-users in the study.

Cardio embolism, a blood clot formed elsewhere in the body that moves to the brain, was most common cause of ischemic stroke in non-marijuana users in the study. Investigators found 29 percent of strokes in non-users were caused by cardio embolism compared to only 14 percent in the marijuana users.

"Fighting stroke must remain a priority, including in young adults," said the authors, led by Valerie Wolff, M.D., PhD. "The first step may be to inform the public regarding the potential occurrence of stroke associated with cannabis and other lifestyle risk factors."


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Materials provided by American College of Cardiology. Note: Content may be edited for style and length.


Journal Reference:

  1. Valérie Wolff, Ielyzaveta Zinchenko, Véronique Quenardelle, Olivier Rouyer, Bernard Geny. Characteristics and Prognosis of Ischemic Stroke in Young Cannabis Users Compared With Non-Cannabis Users. Journal of the American College of Cardiology, 2015; 66 (18): 2052 DOI: 10.1016/j.jacc.2015.08.867

Cite This Page:

American College of Cardiology. "Researchers study differences in ischemic stroke in marijuana users: Stroke in marijuana users more often caused by narrowing of arteries in skull." ScienceDaily. ScienceDaily, 26 October 2015. <www.sciencedaily.com/releases/2015/10/151026172542.htm>.
American College of Cardiology. (2015, October 26). Researchers study differences in ischemic stroke in marijuana users: Stroke in marijuana users more often caused by narrowing of arteries in skull. ScienceDaily. Retrieved May 23, 2017 from www.sciencedaily.com/releases/2015/10/151026172542.htm
American College of Cardiology. "Researchers study differences in ischemic stroke in marijuana users: Stroke in marijuana users more often caused by narrowing of arteries in skull." ScienceDaily. www.sciencedaily.com/releases/2015/10/151026172542.htm (accessed May 23, 2017).

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