Genoscoper Ltd. has published in cooperation with the researchers of University of Helsinki and Pennsylvania (USA) so far the most comprehensive study on canine hereditary disorders. The research brings new information about genetic disorders causing diseases in different dog breeds. The results can be utilized both in dog breeding and veterinary diagnostics. The study was published on PLOS ONE on Aug. 15, 2016.
By testing nearly 7000 dogs representing around 230 different breeds for predisposition to almost 100 genetic disorders, the research team observed that 1 in 6 dogs carried at least one of the tested disease predisposing genetic variants in their genome. Moreover, 1 in 6 of the tested genetic variants was also discovered in a dog breed in which it had not previously been reported in the scientific literature. Through clinical follow up of dogs genetically at risk, the research team was able to confirm that several disorders cause the same disease signs also in other than previously described breeds.
Genetic panel screening delivers results
The study concludes that comprehensive screening for canine inherited disorders represents an efficient and powerful diagnostic and research discovery tool that has a range of applications in veterinary care, disease research, and dog breeding. The authors emphasize that availability of complex DNA-based information is important progress for improvement of the health of purebred dogs, but it should be utilized in combination with other established approaches that promote sustainable breeding and benefit breed health.
Cooperation is key to healthier dogs
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