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Reference Terms
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Brain

Brain refers to the complex organ inside the skull that serves as the command center for the entire nervous system. It’s the most sophisticated biological structure known to science, responsible for everything from basic survival functions—like breathing and heartbeat regulation—to higher-order abilities such as thinking, learning, emotions, creativity, and memory. Packed with about 86 billion neurons, the human brain processes vast amounts of information every second, constantly receiving signals from the body and environment and deciding how to respond.

Structurally, the brain is divided into specialized regions. The cerebrum, the largest part, handles conscious thought, language, and voluntary movement. The cerebellum fine-tunes coordination and balance, while the brainstem controls automatic functions like breathing and heart rate. Other parts, like the hippocampus and amygdala, are key players in memory and emotion. These areas work together through networks of neurons and chemical messengers called neurotransmitters, forming the basis of everything we think and feel.

In science, the brain is a frontier of endless fascination. Neuroscientists study how it develops, how it adapts (a feature called plasticity), and what goes wrong in diseases like Alzheimer’s or Parkinson’s. Cutting-edge fields like neuroimaging and brain-computer interfaces aim to decode brain activity and even connect minds to machines. While we still have much to learn, one thing is clear: the brain isn’t just where we store knowledge—it’s what makes knowledge, experience, and consciousness possible. It’s the ultimate engine behind being human.

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Mind & Brain News

November 27, 2025

Spermine, a small but powerful molecule in the body, helps neutralize harmful protein accumulations linked to Alzheimer’s and Parkinson’s. It encourages these misfolded proteins to gather into manageable clumps that cells can more efficiently ...
Scientists studying young adults with obesity discovered early indicators of brain stress that resemble patterns seen in cognitive impairment. The group showed higher inflammation, signs of liver strain and elevated neurofilament light chain, a ...
A massive veteran study found a strong connection between untreated sleep apnea and a higher chance of Parkinson’s. CPAP users had much lower odds of developing the condition. Researchers believe that repeated dips in oxygen during sleep may ...
Scientists discovered that lowered brain energy signaling in the hippocampus can lead to both depression- and anxiety-like behaviors in mice. Stress reduced ATP, a molecule important for cell energy and communication. Altering a protein called ...
Scientists discovered that more muscle and less hidden abdominal fat are linked to a younger biological brain age. Deep visceral fat appeared to accelerate brain aging, while muscle mass offered a protective ...
Scientists have found that a mutation tied to Alzheimer’s disrupts the production and quality of exosomes—tiny cell-made communication packets. Cells with the defective SORLA protein generate fewer exosomes and ones far less able to support ...
Hypertension begins harming the brain surprisingly early, even before measurable blood pressure increases. Key cells related to blood vessels, signaling, and myelin maintenance begin aging prematurely and malfunctioning. These disruptions resemble ...
Researchers have uncovered a surprising way the brain switches pain on, revealing that neurons can release an enzyme outside the cell that activates pain signals without disrupting normal movement or sensation. This enzyme, called VLK, modifies ...
Researchers discovered that raising the protein Sox9 can help the brain’s astrocytes clear out toxic plaque buildup linked to Alzheimer’s. In mouse models that already showed memory problems, activating these cells improved cognitive ...
Scientists discovered that lowering a specific molecule helps microglia switch into a protective state that quiets brain inflammation in Alzheimer’s. A small group of these cells seems to have an outsized ability to keep the brain healthier. When ...
A new nasal-delivered nanotherapy shows promise against aggressive glioblastoma tumors. By activating the STING immune pathway using gold-core spherical nucleic acids, researchers were able to reach the brain without invasive surgery. When paired ...
Researchers uncovered how estrogen subtly reshapes learning by strengthening dopamine reward signals in the brain. Rats learned faster when estrogen levels were high and struggled when the hormone’s activity was blocked. The findings help explain ...

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