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Hodgkin's lymphoma
Hodgkin's lymphoma, formerly known as Hodgkin's disease, is a type of lymphoma first described by Thomas Hodgkin in 1832. Hodgkin's lymphoma is characterized clinically by the orderly spread of disease from one lymph node group to another and by the development of systemic symptoms with advanced disease. Pathologically, the disease is characterized by the presence of Reed-Sternberg cells. Swollen but painless lymph nodes are the most common sign of Hodgkin's lymphoma, often occurring in the neck. The lymph nodes of the chest are often affected and these may be noticed on a chest X-ray. Hodgkin's lymphoma was one of the first cancers to be rendered curable by combination chemotherapy. Currently, the ABVD chemotherapy regimen is the gold standard for treatment of Hodgkin's disease. With appropriate treatment, over 85% of Hodgkin's lymphoma cases are curable.
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