Aug. 24, 2022 — An engineer has found a way to determine which patients are likely to respond to #CAR T-cell therapy, saving precious time in treating #lymphoma, which is most responsive to this form of ...
June 3, 2022 — Combination chemoimmunotherapy with the Bruton's tyrosine kinase (BTK) inhibitor ibrutinib demonstrated improved progression-free survival over standard chemoimmunotherapy for previously ...
May 25, 2022 — DNA mutations are essential to the rapid development of an array of antibody-producing immune cells called B cells that collectively can recognize a vast number of specific targets. But this process ...
May 12, 2022 — A study investigates the reasons for decreasing remission rates for patients with non-Hodgkin lymphoma treated with chimeric antigen receptor-T cell therapy (CAR-T cell ...
Apr. 28, 2022 — Researchers identify gene expression signatures in different types of lymph nodes cells that play an active role in the development of ...
Mar. 10, 2022 — A recent study followed 515 patients with varying cancers. The goal was to evaluate if patients had an immune response to the Moderna mRNA-1273 vaccine and if that response differed by diagnosis and ...
Feb. 28, 2022 — Researchers have shared a comprehensive multiomics study from a rare cohort of 56 patients with transformed CTCL and identified several genomic alterations and oncogenic programs that may be ...
Jan. 12, 2022 — There are myriad reasons why cancers develop. By studying genes which are altered in people with lymphoma, a multidisciplinary team of researchers has identified a key mechanism involved in disease ...
Jan. 3, 2022 — Aggressive and relatively common lymphomas called diffuse large B cell lymphomas (DLBCLs) have a critical metabolic vulnerability that can be exploited to trick these cancers into starving ...
Dec. 14, 2021 — Driving up the immune response at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice ...
Nov. 4, 2021 — New evidence suggests that adding the targeted therapy ibrutinib (Imbruvica) to a standard chemotherapy regimen can improve how long some younger people with a specific form of diffuse large B-cell ...
Oct. 13, 2021 — For nearly a decade, scientists have known that HIV integrates itself into genes in cells that have the potential to cause cancer. And when this happens in animals with other retroviruses, those ...
Sep. 3, 2021 — Researchers show stem-like T cells within certain lymph nodes could be natural cancer ...
Aug. 24, 2021 — New research has revealed a new fundamental feature of aggressive B-cell lymphomas which could open the door to further research into early detection and treatment of the ...
July 1, 2021 — More than 9 of 10 patients with cancer showed good immune response to the COVID-19 mRNA vaccines after receiving both doses, but subsets of high-risk patients did not, according to a new ...
Apr. 14, 2021 — Researchers have found a long-sought enzyme that prevents cancer by enabling the breakdown of proteins that drive cell growth, and that causes cancer when ...
Apr. 11, 2021 — Early results from a new, pioneering chimeric antigen receptor (CAR) T cell immunotherapy trial found using a bilateral attack achieves a more robust defense and helps avoid ...
Jan. 26, 2021 — Scientists have developed a novel therapy to trick cancer cells into gobbling up what they think is their favorite food - cholesterol -- which actually triggers their destruction. What appears to ...
Jan. 21, 2021 — Researchers have discovered a new enzymatic function of the Epstein-Barr Virus (EBV) protein EBNA1, a critical factor in EBV's ability to transform human cells and cause cancer. Study provides ...
Dec. 17, 2020 — The researchers discovered that cancer immunotherapies that make use of immune system cells such as T cells and CAR-T cells kill not only tumor cells that express the drugs' target, but also ...
