Apr. 11, 2021 Early results from a new, pioneering chimeric antigen receptor (CAR) T cell immunotherapy trial found using a bilateral attack achieves a more robust defense and helps avoid ...
Dec. 17, 2020 The researchers discovered that cancer immunotherapies that make use of immune system cells such as T cells and CAR-T cells kill not only tumor cells that express the drugs' target, but also ...
Dec. 5, 2020 A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical ...
Aug. 18, 2020 Researchers describe a novel acidic niche within lymph nodes that plays an integral role in regulating T cell ...
May 30, 2020 Although lymphoma is one of the most common types of blood cancer, it has a rare subtype for which no effective treatment regimens are known. For the first time, researchers have conducted clinical ...
May 12, 2020 A research team has developed a novel anti-Epstein-Barr virus (EBV) drug that can selectively disrupt a viral protein produced by EBV, leading to the shrinkage of tumors caused by the virus. It is ...
May 5, 2020 In an international collaboration, researchers have mapped the lymph node lymphatic vessels in mice and humans down to the level of individual cells. The results may eventually help scientists to ...
Feb. 20, 2020 Researchers have revealed a new vulnerability in lymphomas that are driven by one of the most common cancer-causing changes in cells. The team hopes that this could be a new target for treating a ...
Jan. 15, 2020 There has been a measurable decline in serious heart conditions among adult survivors of childhood cancer since the 1970s, finds a new ...
Nov. 11, 2019 Researchers compare a lymphoma-dose regimen of rituximab to a rheumatoid arthritis regimen for the treatment of ...
Oct. 28, 2019 A new study has found that the drug first forces itself between the strands of the DNA molecule's double helix, prying them apart. It then compacts the structures by partially neutralizing their ...
Oct. 8, 2019 A new study shows the stage at which lymphoma is originally diagnosed impacts the types of second cancers that may form after ...
Oct. 2, 2019 Investigators analyzed 40 years of cancer burden data and examined patterns of incidence and mortality for various cancers, finding examples for which incidence and mortality moved in concert and ...
Sep. 26, 2019 A cluster of interacting proteins that are active in both human cancers and Tasmanian devil facial tumours, may give clues to how cancers evade the immune system, according to a new ...
Aug. 20, 2019 Scientists have developed a new gene editing system that could be used for anticancer immunotherapy through the simultaneous suppression of proteins that interfere with the immune system expressed on ...
Aug. 8, 2019 New data suggest that people who have a parent, sibling, or child with blood cancer have a higher likelihood of being diagnosed with the ...
Aug. 5, 2019 Researchers have developed a way to use immunotherapy drugs against treatment-resistant non-Hodgkin's lymphomas for the first time by combining them with stem cell transplantation, an approach ...
July 25, 2019 New research shows, surprisingly, that antibiotics inhibit cancer in the skin in patients with rare type of ...
July 25, 2019 Investigators have created a new method that could make immune therapy more effective again brain tumors and expand its use against other types of solid ...
July 22, 2019 Researchers have discovered a hyperactive cell signal that contributes to tumor growth in primary effusion lymphoma, an aggressive type of non-Hodgkin lymphoma caused by infection with the ...