Featured Research

from universities, journals, and other organizations

Nematode Makes Scientific History

Date:
June 4, 1999
Source:
American Phytopathological Society
Summary:
For the first time in history, scientists now have the complete blueprint of the genetic information that makes an animal. British and American scientists, headed by Dr. John Sulston and Dr. Bob Waterston respectively, announced in the 1998 December 11th issue of Science that they completed the sequencing of the whole genome of the tiny soil-dwelling, free-living nematode Caenorhabditis elegans.

St. Paul, MN (June 1, 1999) -- For the first time in history, scientists now have the complete blueprint of the genetic information that makes an animal. British and American scientists, headed by Dr. John Sulston and Dr. Bob Waterston respectively, announced in the 1998 December 11th issue of Science that they completed the sequencing of the whole genome of the tiny soil-dwelling, free-living nematode Caenorhabditis elegans. This landmark biological accomplishment is described on the American Phytopathological Society's feature home page this month at http://www.scisoc.org, which highlights the implications for plant nematology in sequencing C. elegans and contains links to related sites.

Related Articles


"For plant nematologists, this accomplishment represents the beginning of an exciting new chapter in efforts to understand plant-associated nematodes," says Joseph Esnard, a nematologist at Cornell University and member of the American Phytopathological Society and Society of Nematologists. "The sequence provides plant nematologists with a supermarket of nematode genes to shop from."

The completion of sequencing the C. elegans genome is also significant from the point of view that it is the first complete sequence of a multicellular organism. Yeast was the first organism with an organized nucleus to have its genome completely sequenced, but it is single-celled.

Caenorhabditis elegans is a hermaphroditic, non-segmented roundworm-like animal with skin, muscles, and alimentary, nervous, excretory, and reproductive systems. It contains 959 cells, of which neurons make up a third. The C. elegans sequencing consortium estimated the genome size to be approximately 97 million DNA base pairs (on six chromosome pairs) that encode more than 19,000 genes.

Plant nematologists have concentrated their research efforts on plant parasitic nematodes, which are obligate parasites, requiring a host to complete their life cycles. Though C. elegans is not a plant parasite, it is thought to have many of the "same" genes as plant parasitic nematodes. Scientists who worked on the C. elegans genome project claim that 40% of the nematode genes are essentially the same as in humans.

"This revelation bodes well for plant nematologists studying 'parasitism-related' genes in much closer relatives," says Esnard. "The availability of the genome sequence will facilitate molecular cloning of plant parasitic nematode genes by using primers that match nematode sequences of interest. These are exciting times for plant molecular nematologists because, if gene order is highly conserved, simply sequencing regions adjacent to conserved genes will open up treasures. . . and that's just the beginning."

Fabio Piano, a developmental biologist at Cornell University, agrees and adds that new techniques such as RNA interference, which is the inhibition of gene function through RNA injections, could pave the way to functional analyses in many other nematode species. "In turn, these analyses can be geared toward the discovery of essential nematode genes which can be used as targets for nematode control," Piano says.


Story Source:

The above story is based on materials provided by American Phytopathological Society. Note: Materials may be edited for content and length.


Cite This Page:

American Phytopathological Society. "Nematode Makes Scientific History." ScienceDaily. ScienceDaily, 4 June 1999. <www.sciencedaily.com/releases/1999/06/990604080746.htm>.
American Phytopathological Society. (1999, June 4). Nematode Makes Scientific History. ScienceDaily. Retrieved January 29, 2015 from www.sciencedaily.com/releases/1999/06/990604080746.htm
American Phytopathological Society. "Nematode Makes Scientific History." ScienceDaily. www.sciencedaily.com/releases/1999/06/990604080746.htm (accessed January 29, 2015).

Share This


More From ScienceDaily



More Plants & Animals News

Thursday, January 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Dogs Bring on So Many Different Emotions in Their Human Best Friends

Dogs Bring on So Many Different Emotions in Their Human Best Friends

RightThisMinute (Jan. 28, 2015) From new-puppy happy tears to helpful-grocery-carrying-dog laughter, our four-legged best friends can make us feel the entire spectrum of emotions. Video provided by RightThisMinute
Powered by NewsLook.com
Scientists Say Earliest Snakes Lived Alongside The Dinosaurs

Scientists Say Earliest Snakes Lived Alongside The Dinosaurs

Newsy (Jan. 28, 2015) Wrongly categorized as lizard fossils, snake fossils now show the reptile could have developed earlier than we thought — 70 million years earlier. Video provided by Newsy
Powered by NewsLook.com
Malnutrition on the Rise as Violence Flares in C. Africa

Malnutrition on the Rise as Violence Flares in C. Africa

AFP (Jan. 28, 2015) Violence can flare up at any moment in Bambari with only a bridge separating Muslims and Christians. Malnutrition is on the rise and lack of water means simple cooking fires threaten to destroy makeshift camps where people are living. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com
Poultry Culled in Taiwan to Thwart Bird Flu

Poultry Culled in Taiwan to Thwart Bird Flu

Reuters - News Video Online (Jan. 28, 2015) Taiwan culls over a million poultry in efforts to halt various strains of avian flu. Julie Noce reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins