Featured Research

from universities, journals, and other organizations

Protozoan Chosen For Genome Sequencing

Date:
June 4, 2002
Source:
University Of California - Santa Barbara
Summary:
A protozoan that has been studied by a University of California, Santa Barbara scientist for the past 46 years has been assigned high priority for genome sequencing by the National Human Genome Research Institute (NHGRI). Called Tetrahymena, the single-celled organism split off from an ancestor in common with humans about two billion years ago. Yet it carries many of the same genes as humans, and therefore can be used to understand the function of many human genes.

(Santa Barbara, Calif.) –– A protozoan that has been studied by a University of California, Santa Barbara scientist for the past 46 years has been assigned high priority for genome sequencing by the National Human Genome Research Institute (NHGRI).

Related Articles


Called Tetrahymena, the single-celled organism split off from an ancestor in common with humans about two billion years ago. Yet it carries many of the same genes as humans, and therefore can be used to understand the function of many human genes.

Small as it is, Tetrahymena has about 30,000 genes, a similar number as humans. It reproduces quickly, doubling in numbers every two hours, which makes it inexpensive and easy to study. The organism is a ciliate, and uses tiny cilia, like hairs, to propel itself.

Eduardo Orias, research professor of genomics in the Molecular, Cellular and Developmental Biology Department at UC Santa Barbara, submitted a white paper to the NHGRI, on behalf of and with contributions from the international ciliate research community. He also consulted with the Whitehead Institute/MIT Genome Center. (The paper is available on line at http://www.nhgri.nih.gov/DER/Sequencing/Tetrahymena_Genome.pdf). This resulted in Tetrahymena being chosen as a high priority genome for sequencing. (See an NIH announcement at http://www.nhgri.nih.gov/NEWS/sequencing.html.)

Orias began his study of Tetrahymena in 1956, when he was a graduate student at the University of Michigan, and has been working on it virtually ever since. For several

years now his research group at UCSB has been doing genetic and physical mapping of the organism.

Studies of Tetrahymena have made major contributions to genetics and cell biology. For example, scientists used this organism to study the structure of telomeres (ends of chromosomes) and the telomerase enzyme, which has profound importance in cancer and aging.

Sequencing of Tetrahymena will have many benefits, including informing the biology of the causative agent of malaria and other related protist pathogens of great medical or agricultural significance.

Orias, who is the coordinator of the International Tetrahymena Genome

Project, will collaborate in the analysis of the genome sequence and will facilitate the exchange of information and expert advice between the Tetrahymena research community and the sequencing center.

Rat and mouse genome sequencing is approaching completion. In addition to Tetrahymena, NHGRI has chosen (in alphabetical order) chicken, chimpanzee, fungi (various species), honey bee and sea urchin for the next round of sequencing.


Story Source:

The above story is based on materials provided by University Of California - Santa Barbara. Note: Materials may be edited for content and length.


Cite This Page:

University Of California - Santa Barbara. "Protozoan Chosen For Genome Sequencing." ScienceDaily. ScienceDaily, 4 June 2002. <www.sciencedaily.com/releases/2002/06/020604073528.htm>.
University Of California - Santa Barbara. (2002, June 4). Protozoan Chosen For Genome Sequencing. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2002/06/020604073528.htm
University Of California - Santa Barbara. "Protozoan Chosen For Genome Sequencing." ScienceDaily. www.sciencedaily.com/releases/2002/06/020604073528.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Classic Hollywood Memorabilia Goes Under the Hammer

Classic Hollywood Memorabilia Goes Under the Hammer

Reuters - Entertainment Video Online (Nov. 26, 2014) The iconic piano from "Casablanca" and the Cowardly Lion suit from "The Wizard of Oz" fetch millions at auction. Sara Hemrajani reports. Video provided by Reuters
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Feast Your Eyes: Lamb Chop Sent Into Space from UK

Feast Your Eyes: Lamb Chop Sent Into Space from UK

Reuters - Light News Video Online (Nov. 25, 2014) Take a stab at this -- stunt video shows a lamb chop's journey from an east London restaurant over 30 kilometers into space. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins