Featured Research

from universities, journals, and other organizations

Freeze-dried Sperm Can Fertilize Rabbit Oocytes

Date:
March 4, 2004
Source:
Society For The Study Of Reproduction
Summary:
A team of reproductive biologists from the United States and Japan has succeeded in fertilizing rabbit oocytes with "dead" freeze-dried rabbit sperm. The fertilized eggs continued to develop into embryos, some of which were transplanted into female rabbits.

A team of reproductive biologists from the United States and Japan has succeeded in fertilizing rabbit oocytes with "dead" freeze-dried rabbit sperm. The fertilized eggs continued to develop into embryos, some of which were transplanted into female rabbits.

Related Articles


The researchers---from the University of Connecticut, the University of Hawaii, and Hirosaki University---note that rabbit sperm share many similarities with human sperm, so their results suggest that the freeze-drying technique could be used to preserve sperm from humans and many other animal species.

Previously, only freeze-dried sperm from mice had been shown to support embryo development. Mouse sperm, however, are significantly different from sperm of most other mammals because they do not contribute a cellular organelle known as a centrosome to the fertilized oocyte. The question remains whether the centrosomes in rabbit sperm survive the freeze-drying or whether centrosomes are not essential for embryos of mammals to develop.

Freeze-drying immobilizes rabbit sperm, breaks plasma membranes, and causes fragmentation of the sperm tails. Nonetheless, the chromosomes remain intact in the "dead" sperm. Even after being stored at temperatures above freezing for more than two years, the treated sperm were as capable as fresh sperm at fertilizing rabbit oocytes.

In a paper scheduled for publication in Biology of Reproduction, the team headed by Xiangzhong Yang of the Center for Regenerative Biology at the University of Connecticut, Storrs, and Ryuzo Yanagimachi of the University of Hawaii Medical School, Honolulu, reports that one rabbit pup was born after 230 oocytes fertilized with freeze-dried sperm were transferred to 8 female rabbits. The full-term pup appeared normal but was still-born, a common outcome of single-birth pregnancies in rabbits.

The researchers believe that improvements in their procedure will someday enable freeze-dried sperm of mammalian species to be stored indefinitely at room temperatures.

Biology of Reproduction, published by the Society for the Study of Reproduction, is the top-rated peer-reviewed journal in the field of reproductive biology.


Story Source:

The above story is based on materials provided by Society For The Study Of Reproduction. Note: Materials may be edited for content and length.


Cite This Page:

Society For The Study Of Reproduction. "Freeze-dried Sperm Can Fertilize Rabbit Oocytes." ScienceDaily. ScienceDaily, 4 March 2004. <www.sciencedaily.com/releases/2004/03/040304071741.htm>.
Society For The Study Of Reproduction. (2004, March 4). Freeze-dried Sperm Can Fertilize Rabbit Oocytes. ScienceDaily. Retrieved January 30, 2015 from www.sciencedaily.com/releases/2004/03/040304071741.htm
Society For The Study Of Reproduction. "Freeze-dried Sperm Can Fertilize Rabbit Oocytes." ScienceDaily. www.sciencedaily.com/releases/2004/03/040304071741.htm (accessed January 30, 2015).

Share This


More From ScienceDaily



More Plants & Animals News

Friday, January 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Brawling Pandas Are Violently Adorable

Brawling Pandas Are Violently Adorable

Buzz60 (Jan. 29, 2015) Video of pandas play fighting at the Chengdu Research Base in China will make your day. Mara Montalbano (@maramontalbano) shows us. Video provided by Buzz60
Powered by NewsLook.com
Why Researchers Say We Should Cut Back On Biofuels

Why Researchers Say We Should Cut Back On Biofuels

Newsy (Jan. 29, 2015) Biofuels aren&apos;t the best alternative to fossil fuels, according to a new report. In fact, they&apos;re quite a bad one. Video provided by Newsy
Powered by NewsLook.com
3-D Printed Wheelchair Helps Two-Legged Dog Learn to Run

3-D Printed Wheelchair Helps Two-Legged Dog Learn to Run

Buzz60 (Jan. 29, 2015) 3-D printing helps another two-legged dog run around with his four-legged friends. Jen Markham (@jenmarkham) has the adorable video. Video provided by Buzz60
Powered by NewsLook.com
Dogs Bring on So Many Different Emotions in Their Human Best Friends

Dogs Bring on So Many Different Emotions in Their Human Best Friends

RightThisMinute (Jan. 28, 2015) From new-puppy happy tears to helpful-grocery-carrying-dog laughter, our four-legged best friends can make us feel the entire spectrum of emotions. Video provided by RightThisMinute
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins