Featured Research

from universities, journals, and other organizations

Medicinal Compound Gets New Life As Fungicide

Date:
April 7, 2005
Source:
USDA / Agricultural Research Service
Summary:
Growers of many fruit and ornamental crops have new weapons for fighting destructive fungi, thanks to Agricultural Research Service (ARS) and University of Mississippi (UM) scientists who've transformed a medicinal compound into an agricultural fungicide.

Plant pathologist Deborah Fravel observes growth of the plant-pathogenic strain of Fusarium oxysporum that causes fusarium wilt.
Credit: Photo by Keith Weller

Growers of many fruit and ornamental crops have new weapons for fighting destructive fungi, thanks to Agricultural Research Service (ARS) and University of Mississippi (UM) scientists who've transformed a medicinal compound into an agricultural fungicide.

Related Articles


The naturally occurring compound, called sampangine, was first patented by UM in 1990 as a treatment for human fungal infections. It was never released pharmaceutically.

Now, plant pathologist David Wedge of ARS' Natural Products Utilization Research Unit and UM associate professor Dale Nagle have been issued a patent for sampangine and similar, related compounds as broad-spectrum, low-toxicity controls of fungal plant pathogens that threaten agriculture.

The ARS unit and the university are both based in Oxford, Miss. ARS is the U.S. Department of Agriculture's chief scientific research agency.

According to the new patent--US No. 6,844,353--sampangine-based compounds can control such fungi as Botrytis cinerea, which causes gray mold on tomatoes; Colletotrichum fragariae, which produces anthracnose crown rot and wilt in strawberry plants; C. gloeosporioides, which sickens numerous plants, including grapes, strawberry, citrus and papaya; and Fusarium oxysporum, which induces vascular wilt in crops such as potato, sugarcane and many ornamentals.

Plant pathologist Barbara Smith of the ARS Small Fruits Research Station in Poplarville, Miss., helped evaluate the effectiveness of the compounds against strawberry anthracnose.

Sampangine can greatly help the United States' $31-billion-a-year minor crop industry. For example, in recent studies in Louisiana, Wedge and Smith verified that some Botrytis fungal strains now resist fungicides commonly used against these strains.

According to Wedge, sampangine shows potential for managing fungicide resistance against important diseases and augmenting use of fungicides that are vulnerable to resistance. The sampangine-based fungicides may also find use as postharvest and antidecay agents.

This work is also the focus of a cooperative research and development agreement between ARS and Icoria Inc., a North Carolina biotechnology firm. The agreement calls for work toward determining sampangine's modes of action, and identifying additional related compounds with commercial potential for managing agriculturally important plant-pathogenic fungi.


Story Source:

The above story is based on materials provided by USDA / Agricultural Research Service. Note: Materials may be edited for content and length.


Cite This Page:

USDA / Agricultural Research Service. "Medicinal Compound Gets New Life As Fungicide." ScienceDaily. ScienceDaily, 7 April 2005. <www.sciencedaily.com/releases/2005/03/050325184746.htm>.
USDA / Agricultural Research Service. (2005, April 7). Medicinal Compound Gets New Life As Fungicide. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2005/03/050325184746.htm
USDA / Agricultural Research Service. "Medicinal Compound Gets New Life As Fungicide." ScienceDaily. www.sciencedaily.com/releases/2005/03/050325184746.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Classic Hollywood Memorabilia Goes Under the Hammer

Classic Hollywood Memorabilia Goes Under the Hammer

Reuters - Entertainment Video Online (Nov. 26, 2014) The iconic piano from "Casablanca" and the Cowardly Lion suit from "The Wizard of Oz" fetch millions at auction. Sara Hemrajani reports. Video provided by Reuters
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Feast Your Eyes: Lamb Chop Sent Into Space from UK

Feast Your Eyes: Lamb Chop Sent Into Space from UK

Reuters - Light News Video Online (Nov. 25, 2014) Take a stab at this -- stunt video shows a lamb chop's journey from an east London restaurant over 30 kilometers into space. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins