Featured Research

from universities, journals, and other organizations

Scientists Develop Fungus-fighting Vaccine

Date:
September 5, 2005
Source:
Journal of Experimental Medicine
Summary:
A group of scientists in Italy have developed a vaccine with the potential to protect against fungal pathogens that commonly infect humans, according to a study by Torosantucci and colleagues in the September 5 issue of The Journal of Experimental Medicine. Although these fungi pose little threat to people with healthy immune systems, they can cause fatal infections in those whose immune systems have been weakened by cancer treatments or post-transplant immunosuppressive therapies.

Related Articles


Although these fungi pose little threat to people with healthy immunesystems, they can cause fatal infections in those whose immune systemshave been weakened by cancer treatments or post-transplantimmunosuppressive therapies. No anti-fungal vaccines are currentlyavailable.

The new vaccine was made of a sugar-like molecule called beta-glucanthat is found on the cell wall of the fungus and that the fungus needsto grow and survive. To induce a robust immune response to the vaccine,the group attached the relatively innocuous beta-glucan to a proteincalled diptheria toxin that is known to stimulate the immune system andhas been used in other human vaccines.

The vaccine protected rodents from fatal fungal infections bytriggering the production of anti-beta-glucan antibodies. Theseantibodies stuck to the invading fungal cell wall and prevented thefungus from growing. The authors now plan to test the vaccine in humansand hope the results are equally promising.


Story Source:

The above story is based on materials provided by Journal of Experimental Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Journal of Experimental Medicine. "Scientists Develop Fungus-fighting Vaccine." ScienceDaily. ScienceDaily, 5 September 2005. <www.sciencedaily.com/releases/2005/09/050905112231.htm>.
Journal of Experimental Medicine. (2005, September 5). Scientists Develop Fungus-fighting Vaccine. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2005/09/050905112231.htm
Journal of Experimental Medicine. "Scientists Develop Fungus-fighting Vaccine." ScienceDaily. www.sciencedaily.com/releases/2005/09/050905112231.htm (accessed October 25, 2014).

Share This



More Plants & Animals News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Reuters - Innovations Video Online (Oct. 24, 2014) Miniature deep sea animals discovered off the Australian coast almost three decades ago are puzzling scientists, who say the organisms have proved impossible to categorise. Academics at the Natural History of Denmark have appealed to the world scientific community for help, saying that further information on Dendrogramma enigmatica and Dendrogramma discoides could answer key evolutionary questions. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Black Bear Cub Goes Sunday Shopping

Black Bear Cub Goes Sunday Shopping

Reuters - Light News Video Online (Oct. 23, 2014) Price check on honey? Bear cub startles Oregon drugstore shoppers. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Dances With Wolves in China's Wild West

Dances With Wolves in China's Wild West

AFP (Oct. 23, 2014) One man is on a mission to boost the population of wolves in China's violence-wracked far west. The animal - symbol of the Uighur minority there - is under threat with a massive human resettlement program in the region. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins