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New Technique Adds Precision And Permanence To Gene Therapy

Date:
October 11, 2005
Source:
The Mount Sinai Hospital / Mount Sinai School of Medicine
Summary:
Mount Sinai School of Medicine researchers developed a technique for inserting genes into specific sites on the genome in liver cells. The genes are inserted into non-coding regions of the genome so there is no danger of interfering with the functioning of other genes. Once inserted, the gene remains a permanent part of the cell's genome. In a study published in this week's PNAS, the researchers used this technique to cure phenylketonuria (PKU) in mice.

Mount Sinai School of Medicine researchers developed a technique for inserting genes into specific sites on the genome in liver cells. The genes are inserted into non-coding regions of the genome so there is no danger of interfering with the functioning of other genes. Once inserted, the gene remains a permanent part of the cell's genome. In a study published in this week's PNAS, the researchers used this technique to cure phenylketonuria (PKU) in mice.


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The above story is based on materials provided by The Mount Sinai Hospital / Mount Sinai School of Medicine. Note: Materials may be edited for content and length.


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The Mount Sinai Hospital / Mount Sinai School of Medicine. "New Technique Adds Precision And Permanence To Gene Therapy." ScienceDaily. ScienceDaily, 11 October 2005. <www.sciencedaily.com/releases/2005/10/051011001005.htm>.
The Mount Sinai Hospital / Mount Sinai School of Medicine. (2005, October 11). New Technique Adds Precision And Permanence To Gene Therapy. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2005/10/051011001005.htm
The Mount Sinai Hospital / Mount Sinai School of Medicine. "New Technique Adds Precision And Permanence To Gene Therapy." ScienceDaily. www.sciencedaily.com/releases/2005/10/051011001005.htm (accessed April 24, 2014).

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