Featured Research

from universities, journals, and other organizations

Interactive 3-D Atlas Of Mouse Brain Now Available On Web

Date:
December 1, 2005
Source:
Brookhaven National Laboratory
Summary:
Researchers at the US Department of Energy's Brookhaven National Laboratory have just launched a web-based 3-D digital atlas browser and database of the brain of a popular laboratory mouse. Neuroscientists around the world can now download these extremely accurate anatomical templates and use them to map other data -- such as which parts of the brain are metabolically active and where particular genes are expressed -- and for making quantitative anatomical comparisons with other, genetically engineered mouse strains.

3-D digital rendering of the adult C57BL/6J mouse brain.
Credit: Image courtesy of Brookhaven National Laboratory

Researchers at the U.S. Department of Energy's Brookhaven National Laboratory have just launched a web-based 3-D digital atlas browser and database of the brain of a popular laboratory mouse (see http://www.bnl.gov/CTN/mouse/).

Related Articles


"Neuroscientists around the world can now download these extremely accurate anatomical templates and use them to map other data -- such as which parts of the brain are metabolically active and where particular genes are expressed -- and for making quantitative anatomical comparisons with other, genetically engineered mouse strains," said project leader Helene Benveniste, who is a researcher in Brookhaven's medical department and a professor of anesthesiology at Stony Brook University.

The database was created using high-resolution magnetic resonance (MR) microscopy at the University of Florida in collaboration with researchers from Brookhaven Lab's Center for Translational Neuroimaging. The work was done in parallel with an international collaboration, the Mouse Phenome Database (MPD) project, which was created to establish a collection of baseline phenotypic data from commonly used inbred mice.

The new brain atlas database consists of 3-D anatomical data from 10 adult male mice of the strain C57BL/6J, and contains data on 20 segmented structures, including variability of brain structures across the strain, and downloadable visualization tools.

The research that makes up this database was published as a cover article in the October 2005 issue of the journal Neuroscience.

###

This research was initially funded by the National Institute on Drug Abuse and then by the National Institute of Biomedical Imaging and Bioengineering (NIBIB). The development of the web-browser and database was supported by both NIBIB and the Office of Biological and Environmental Research within the U.S. Department of Energy's Office of Science. A variety of brain-imaging techniques including magnetic resonance imaging are a direct outgrowth of DOE's support of basic physics research.

One of the ten national laboratories overseen and primarily funded by the Office of Science of the U.S. Department of Energy (DOE), Brookhaven National Laboratory conducts research in the physical, biomedical, and environmental sciences, as well as in energy technologies and national security. Brookhaven Lab also builds and operates major scientific facilities available to university, industry and government researchers. Brookhaven is operated and managed for DOE's Office of Science by Brookhaven Science Associates, a limited-liability company founded by Stony Brook University, the largest academic user of Laboratory facilities, and Battelle, a nonprofit, applied science and technology organization. Visit Brookhaven Lab's electronic newsroom for links, news archives, graphics, and more: http://www.bnl.gov/newsroom


Story Source:

The above story is based on materials provided by Brookhaven National Laboratory. Note: Materials may be edited for content and length.


Cite This Page:

Brookhaven National Laboratory. "Interactive 3-D Atlas Of Mouse Brain Now Available On Web." ScienceDaily. ScienceDaily, 1 December 2005. <www.sciencedaily.com/releases/2005/11/051130230725.htm>.
Brookhaven National Laboratory. (2005, December 1). Interactive 3-D Atlas Of Mouse Brain Now Available On Web. ScienceDaily. Retrieved October 30, 2014 from www.sciencedaily.com/releases/2005/11/051130230725.htm
Brookhaven National Laboratory. "Interactive 3-D Atlas Of Mouse Brain Now Available On Web." ScienceDaily. www.sciencedaily.com/releases/2005/11/051130230725.htm (accessed October 30, 2014).

Share This



More Plants & Animals News

Thursday, October 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Galapagos Tortoises Bounce Back, But Ecosystem Lags

Galapagos Tortoises Bounce Back, But Ecosystem Lags

Newsy (Oct. 29, 2014) The Galapagos tortoise has made a stupendous recovery from the brink of extinction to a population of more than 1,000. But it still faces threats. Video provided by Newsy
Powered by NewsLook.com
Can Drinking Milk Lead To Early Death?

Can Drinking Milk Lead To Early Death?

Newsy (Oct. 29, 2014) Researchers in Sweden released a study showing heavy milk drinkers face an increased mortality risk from a variety of causes. Video provided by Newsy
Powered by NewsLook.com
Obama: The US Will Not 'run and Hide' From Ebola

Obama: The US Will Not 'run and Hide' From Ebola

AP (Oct. 29, 2014) Surrounded by health care workers in the White House East Room, President Barack Obama said the U.S. will likely see additional Ebola cases in the weeks ahead. But he said the nation can't seal itself off in the fight against the disease. (Oct. 29) Video provided by AP
Powered by NewsLook.com
Oatmeal Healthy Recipes and Benefits

Oatmeal Healthy Recipes and Benefits

Buzz60 (Oct. 29, 2014) Oatmeal is a fantastic way to start your day. Whichever way you prepare them, oats provide your body with many health benefits. In celebration of National Oatmeal Day, Krystin Goodwin (@krystingoodwin) has a few recipe ideas, and tips on how to kickstart your day with this wholesome snack! Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins