Featured Research

from universities, journals, and other organizations

Cup Of Green Tea To Keep The Bacteria Away

Date:
January 16, 2007
Source:
National Institute Of Chemistry, Slovenia
Summary:
Beneficial effects of green tea have been known for millenia, particularly in Asian cultures. An ancient Chinese proverb says: "Better to be deprived of food for three days, than tea for one". A cup of green tea contains up to 200 mg of catechins, whose biological activity has been mainly attributed to its antioxidant activity. Efficiency of green tea extract in oral hygiene has been known for centuries and this gave researchers a clue that antibacterial activity might be involved.

Beneficial effects of green tea have been known for millenia, particularly in Asian cultures. An ancient Chinese proverb says: "Better to be deprived of food for three days, than tea for one". A cup of green tea contains up to 200 mg of catechins, whose biological activity has been mainly attributed to its antioxidant activity. Efficiency of green tea extract in oral hygiene has been known for centuries and this gave researchers a clue that antibacterial activity might be involved.

Now researchers from the National institute of Chemistry in Ljubljana, Slovenia discovered that the main ingredients of green tea are able to perform other tricks. They found out that green tea catechins inhibit essential bacterial enzyme DNA gyrase, which is the target of several existing clinically used drugs. By the use of NMR spectroscopy, researchers from Slovenia have now pinpointed the ATP-binding site of DNA gyrase as target of EGCG, the most abundant catechin from the green tea extract. Up to now several compounds targeted against the ATP-binding site of bacteria gyrase have been known but couldn't be used as drugs due to their side effects on mammalian cells.

Lead researcher Roman Jerala, the head of the Laboratory of Biotechnology at NIC explains: "We can anticipate to avoid the problem of toxicity using the compounds based on the green tea catechins, which have centuries of established safety record in the human diet."

This finding may be used to develop even more potent antibacterial compounds. Results were recently published in the Journal of Medicinal Chemistry.


Story Source:

The above story is based on materials provided by National Institute Of Chemistry, Slovenia. Note: Materials may be edited for content and length.


Cite This Page:

National Institute Of Chemistry, Slovenia. "Cup Of Green Tea To Keep The Bacteria Away." ScienceDaily. ScienceDaily, 16 January 2007. <www.sciencedaily.com/releases/2007/01/070116132946.htm>.
National Institute Of Chemistry, Slovenia. (2007, January 16). Cup Of Green Tea To Keep The Bacteria Away. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2007/01/070116132946.htm
National Institute Of Chemistry, Slovenia. "Cup Of Green Tea To Keep The Bacteria Away." ScienceDaily. www.sciencedaily.com/releases/2007/01/070116132946.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Generics Eat Into Pfizer's Sales

Generics Eat Into Pfizer's Sales

Reuters - Business Video Online (July 29, 2014) Pfizer, the world's largest drug maker, cut full-year revenue forecasts because generics could cut into sales of its anti-arthritis drug, Celebrex. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Nigeria Ups Ebola Stakes on 1st Death

Nigeria Ups Ebola Stakes on 1st Death

Reuters - Business Video Online (July 29, 2014) Nigerian authorities have shut and quarantined a Lagos hospital where a Liberian man died of the Ebola virus, the first recorded case of the highly-infectious disease in Africa's most populous economy. David Pollard reports Video provided by Reuters
Powered by NewsLook.com
Running 5 Minutes A Day Might Add Years To Your Life

Running 5 Minutes A Day Might Add Years To Your Life

Newsy (July 29, 2014) According to a new study, just five minutes of running or jogging a day could add years to your life. Video provided by Newsy
Powered by NewsLook.com
Ebola Outbreak Poses Little Threat To U.S.: CDC

Ebola Outbreak Poses Little Threat To U.S.: CDC

Newsy (July 29, 2014) The Ebola outbreak in West Africa poses little threat to Americans, according to officials with the Centers for Disease Control and Prevention. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins