Featured Research

from universities, journals, and other organizations

Toward A New Generation Of Vaccines For Malaria And Other Diseases

Date:
March 28, 2008
Source:
American Chemical Society
Summary:
Researchers have a new strategy for designing the next generation of synthetic vaccines that could lead to more effective treatments for fighting malaria, tuberculosis, AIDS and other infectious diseases. These conditions kill more than 17 million people around the world each year.

Scientists have identified key protein fragments in infectious diseases and are reporting a strategy that could usher in more effective vaccines.
Credit: Courtesy of Queensland Health

Researchers in Colombia, South America, describe a new strategy for designing the next generation of synthetic vaccines that could lead to more effective treatments for fighting malaria, tuberculosis, AIDS and other infectious diseases. These conditions kill more than 17 million people around the world each year.

Traditional vaccine development involves the use of microorganisms to trigger an immune response by the body. However, this approach can produce unwanted side effects and may be ineffective against microbes with extremely complex infection cycles. Therefore, researchers agree on the need for better vaccine.

In the study, Manuel E. Patarroyo and his son Manuel A. Patarroyo describe a completely new strategy for designing more effective vaccines, which are chemically synthesized in the laboratory without the use of microorganisms. They identified dozens of key protein fragments involved in the complex infection process of the malaria parasite, from which they designed, specifically modified and synthesized chemically some of the most promising malaria vaccine candidates that have been tested to date.

Likewise, identifying the disease-related protein fragments involved in the complex infection process of other transmittable diseases could result in new, more effective vaccines to help fight these diseases, the scientists say. They also note that this innovative approach establishes for the first time the emerging rules for the development of vaccines against diseases scourging humankind.

The study "Emerging Rules for Subunit-Based Multiantigenic, Multistage Chemically Synthesized Vaccines" appears in the current issue of ACS' Accounts of Chemical Research (http://dx.doi.org/10.1021/ar700120t)


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Cite This Page:

American Chemical Society. "Toward A New Generation Of Vaccines For Malaria And Other Diseases." ScienceDaily. ScienceDaily, 28 March 2008. <www.sciencedaily.com/releases/2008/03/080324090552.htm>.
American Chemical Society. (2008, March 28). Toward A New Generation Of Vaccines For Malaria And Other Diseases. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2008/03/080324090552.htm
American Chemical Society. "Toward A New Generation Of Vaccines For Malaria And Other Diseases." ScienceDaily. www.sciencedaily.com/releases/2008/03/080324090552.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC Revamps Ebola Guidelines After Criticism

CDC Revamps Ebola Guidelines After Criticism

Newsy (Oct. 21, 2014) The Centers for Disease Control and Prevention have issued new protocols for healthcare workers interacting with Ebola patients. Video provided by Newsy
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
CDC Issues New Ebola Guidelines for Health Workers

CDC Issues New Ebola Guidelines for Health Workers

Reuters - US Online Video (Oct. 21, 2014) The U.S. Centers for Disease Control and Prevention has set up new guidelines for health workers taking care of patients infected with Ebola. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
'Cadaver Dog' Sniffs out Human Remains

'Cadaver Dog' Sniffs out Human Remains

AP (Oct. 21, 2014) Where's a body buried? Buster's nose can often tell you. He's a cadaver dog, specially trained to find human remains and increasingly being used by law enforcement and accepted in courts. These dogs are helping solve even decades-old mysteries. (Oct. 21) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins