Featured Research

from universities, journals, and other organizations

New Method For Directing And Filming Blood Vessels Developed

Date:
March 28, 2008
Source:
Uppsala University
Summary:
A new method of filming blood-vessel cells that move in accordance with targeted signals has been developed. The method can also be used to study how migration of cancer cells and nerves can be controlled. Formation of new blood cells and lymph vessels takes place with a number of different diseases.

A new method of filming blood-vessel cells that move in accordance with targeted signals has been developed by researchers at Uppsala University in collaboration with researchers at the University of California. The method can also be used to study how migration of cancer cells and nerves can be controlled.

Formation of new blood cells and lymph vessels takes place with a number of different diseases. Formation of new cells is sometimes desirable, e.g. in the event of wound healing, when new tissue must be formed. Undesirable vessel formation takes place in the event of tumour growth. The tumour receives nutrition from the new blood vessels and can also spread via newly formed lymph vessels, thus prevention of vessel growth is desirable in this situation.

A major challenge in the field of medicine is understanding the signals governing the way vessels are formed. It has been proposed that targeted signals -- so-called gradients -- from growth factors instruct the vessels as to the direction in which they are to grow.

"Our study shows that a simple gradient from a signal protein is sufficient to tell the blood vessel cell in which direction it is to move. We have also been able to show that the form of the gradient governs the way in which the cell moves," says Irmeli Barkefors, a postgraduate student at Uppsala University.

The research group is now going to develop the method further. The aim is to be able to study targeted migration in complicated organ culture systems, whereby interaction between different cell types can be studied.

"The method can basically be adapted to facilitate study of all types of cells. It is particularly important to study the mechanisms that determine whether or not cancer cells spread," says researchers Johan Kreuger, who has been heading the project.

The study was published on 17 March in the Internet edition of the Journal of Biological Chemistry. (http://www.jbc.org/cgi/content/abstract/M704917200v1)


Story Source:

The above story is based on materials provided by Uppsala University. Note: Materials may be edited for content and length.


Cite This Page:

Uppsala University. "New Method For Directing And Filming Blood Vessels Developed." ScienceDaily. ScienceDaily, 28 March 2008. <www.sciencedaily.com/releases/2008/03/080326111646.htm>.
Uppsala University. (2008, March 28). New Method For Directing And Filming Blood Vessels Developed. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2008/03/080326111646.htm
Uppsala University. "New Method For Directing And Filming Blood Vessels Developed." ScienceDaily. www.sciencedaily.com/releases/2008/03/080326111646.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com
Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins