Featured Research

from universities, journals, and other organizations

New Method For Directing And Filming Blood Vessels Developed

Date:
March 28, 2008
Source:
Uppsala University
Summary:
A new method of filming blood-vessel cells that move in accordance with targeted signals has been developed. The method can also be used to study how migration of cancer cells and nerves can be controlled. Formation of new blood cells and lymph vessels takes place with a number of different diseases.

A new method of filming blood-vessel cells that move in accordance with targeted signals has been developed by researchers at Uppsala University in collaboration with researchers at the University of California. The method can also be used to study how migration of cancer cells and nerves can be controlled.

Formation of new blood cells and lymph vessels takes place with a number of different diseases. Formation of new cells is sometimes desirable, e.g. in the event of wound healing, when new tissue must be formed. Undesirable vessel formation takes place in the event of tumour growth. The tumour receives nutrition from the new blood vessels and can also spread via newly formed lymph vessels, thus prevention of vessel growth is desirable in this situation.

A major challenge in the field of medicine is understanding the signals governing the way vessels are formed. It has been proposed that targeted signals -- so-called gradients -- from growth factors instruct the vessels as to the direction in which they are to grow.

"Our study shows that a simple gradient from a signal protein is sufficient to tell the blood vessel cell in which direction it is to move. We have also been able to show that the form of the gradient governs the way in which the cell moves," says Irmeli Barkefors, a postgraduate student at Uppsala University.

The research group is now going to develop the method further. The aim is to be able to study targeted migration in complicated organ culture systems, whereby interaction between different cell types can be studied.

"The method can basically be adapted to facilitate study of all types of cells. It is particularly important to study the mechanisms that determine whether or not cancer cells spread," says researchers Johan Kreuger, who has been heading the project.

The study was published on 17 March in the Internet edition of the Journal of Biological Chemistry. (http://www.jbc.org/cgi/content/abstract/M704917200v1)


Story Source:

The above story is based on materials provided by Uppsala University. Note: Materials may be edited for content and length.


Cite This Page:

Uppsala University. "New Method For Directing And Filming Blood Vessels Developed." ScienceDaily. ScienceDaily, 28 March 2008. <www.sciencedaily.com/releases/2008/03/080326111646.htm>.
Uppsala University. (2008, March 28). New Method For Directing And Filming Blood Vessels Developed. ScienceDaily. Retrieved August 28, 2014 from www.sciencedaily.com/releases/2008/03/080326111646.htm
Uppsala University. "New Method For Directing And Filming Blood Vessels Developed." ScienceDaily. www.sciencedaily.com/releases/2008/03/080326111646.htm (accessed August 28, 2014).

Share This




More Health & Medicine News

Thursday, August 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mini Pacemaker Has No Wires

Mini Pacemaker Has No Wires

Ivanhoe (Aug. 27, 2014) Cardiac experts are testing a new experimental device designed to eliminate major surgery and still keep the heart on track. Video provided by Ivanhoe
Powered by NewsLook.com
After Cancer: Rebuilding Breasts With Fat

After Cancer: Rebuilding Breasts With Fat

Ivanhoe (Aug. 27, 2014) More than 269 million women are diagnosed with breast cancer each year. Many of them will need surgery and radiation, but there’s a new simple way to reconstruct tissue using a patient’s own fat. Video provided by Ivanhoe
Powered by NewsLook.com
Blood Clots in Kids

Blood Clots in Kids

Ivanhoe (Aug. 27, 2014) Every year, up to 200,000 Americans die from a blood clot that travels to their lungs. You’ve heard about clots in adults, but new research shows kids can get them too. Video provided by Ivanhoe
Powered by NewsLook.com
Radio Waves Knock out Knee Pain

Radio Waves Knock out Knee Pain

Ivanhoe (Aug. 27, 2014) Doctors have used radio frequency ablation or RFA to reduce neck and back pain for years. But now, that same technique is providing longer-term relief for patients with severe knee pain. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins