Featured Research

from universities, journals, and other organizations

Genetic Predisposition May Play A Role In Anxiety Disorders

Date:
August 27, 2008
Source:
Academy of Finland
Summary:
Finnish scientists have identified genes that may predispose to anxiety disorders. Some of the studied genes show a statistical association with specific anxiety disorders.

Finnish scientists have identified genes that may predispose to anxiety disorders. Research conducted under the supervision of Academy Research Fellow Iiris Hovatta have focused on genes that influence human behaviour, and some of the studied genes show a statistical association with specific anxiety disorders.

Previously Hovatta's team have explored the genetic background of anxiety in experimental models. The current study follows up on these findings in humans using data collected as part of national Health 2000 Survey consisting of 321 individuals who had been diagnosed with anxiety disorder and 653 healthy controls. Hovatta says it was interesting that different genes showed evidence for association to specific types of anxiety disorders, such as panic disorder, social phobias or generalised anxiety disorder. The results will be published in Biological Psychiatry in October.

"Environmental factors, such as stressful life events, may trigger an anxiety disorder more easily in people who have a genetic predisposition to the illness," Iiris Hovatta says. The focus in the team's further studies will be to understand the molecular and cellular processes that link these genes to the regulation of anxiety behaviour.

Furthermore, the team's international collaborators in Spain and the United States are trying to replicate these findings in their anxiety disorder datasets to see whether the genes identified by Finnish scientists predispose to anxiety disorders in other populations as well. Only by replicating the results firm conclusions can be drawn about the role of these genes in the predisposition to anxiety in more general.

A closer understanding of the genetics and neurobiology of anxiety disorders is expected to help improve treatment of the illness using both drugs and therapy-based approaches. For the time being, no targeted drugs are available for the treatment of anxiety disorders. Some patients with anxiety disorders do benefit from the currently used medication, but about half of the patients do not.

The work is carried out as part of the Academy of Finland Research Programme on Neuroscience (NEURO).


Story Source:

The above story is based on materials provided by Academy of Finland. Note: Materials may be edited for content and length.


Journal Reference:

  1. Donner et al. An Association Analysis of Murine Anxiety Genes in Humans Implicates Novel Candidate Genes for Anxiety Disorders. Biological Psychiatry, 2008; DOI: 10.1016/j.biopsych.2008.06.002

Cite This Page:

Academy of Finland. "Genetic Predisposition May Play A Role In Anxiety Disorders." ScienceDaily. ScienceDaily, 27 August 2008. <www.sciencedaily.com/releases/2008/08/080827100818.htm>.
Academy of Finland. (2008, August 27). Genetic Predisposition May Play A Role In Anxiety Disorders. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2008/08/080827100818.htm
Academy of Finland. "Genetic Predisposition May Play A Role In Anxiety Disorders." ScienceDaily. www.sciencedaily.com/releases/2008/08/080827100818.htm (accessed July 30, 2014).

Share This




More Mind & Brain News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

It's Not Just Facebook: OKCupid Experiments With Users Too

It's Not Just Facebook: OKCupid Experiments With Users Too

Newsy (July 29, 2014) If you've been looking for love online, there's a chance somebody has been looking at how you're looking. Video provided by Newsy
Powered by NewsLook.com
How Your Face Can Leave A Good Or Bad First Impression

How Your Face Can Leave A Good Or Bad First Impression

Newsy (July 29, 2014) Researchers have found certain facial features can make us seem more attractive or trustworthy. Video provided by Newsy
Powered by NewsLook.com
Losing Sleep Leaves You Vulnerable To 'False Memories'

Losing Sleep Leaves You Vulnerable To 'False Memories'

Newsy (July 27, 2014) A new study shows sleep deprivation can make it harder for people to remember specific details of an event. Video provided by Newsy
Powered by NewsLook.com
University Quiz Implies Atheists Are Smarter Than Christians

University Quiz Implies Atheists Are Smarter Than Christians

Newsy (July 25, 2014) An online quiz from a required course at Ohio State is making waves for suggesting atheists are inherently smarter than Christians. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins