Featured Research

from universities, journals, and other organizations

Good Results For New Vaccine Against Horse Strangles Disease

Date:
October 8, 2009
Source:
The Swedish Research Council
Summary:
Tests show good results for a new vaccine against horse strangles disease. In time this may also lead to new vaccines against human diseases.

Horse suffering from strangles.
Credit: Animal Health Trust

A research group at the Department of Microbiology, Swedish University of Agricultural Sciences (SLU) in Uppsala, Sweden has – in collaboration with J-I Flock’s research group at the Karolinska Institutet medical university in Stockholm, the pharmacological company Intervacc AB, Stockholm and the Animal Health Trust in the UK – after many years of research made a breakthrough in finding a vaccine against the horse disease strangles.

Related Articles


Strangles is a most contagious disease caused by the bacteria Streptococcus equi. The disease results in high fever and characteristically swollen lymphoid glands in the neck region generating large boils that often burst. Most contaminated horses recover and become immune against the disease, but in worst cases strangles can be fatal. A stable where strangles has been discovered must be put in quarantine causing economical losses and practical problems. The disease is spread worldwide; in Sweden some 100 cases are reported annually, in the UK circa 1,000 cases per year are reported.

Today there exists no safe and efficient vaccine against strangles, and previous vaccines are based on live bacteria, which is hazardous and may cause severe side effects. The new vaccine is based on pure proteins produced by recombinant DNA technology. The vaccine consists of seven different Streptococcus proteins, and the results from injecting horses have been most positive so far, i.e. the vaccine is highly protective and has shown no side effects.

The goal is to have the new strangles vaccine commercially available in a near future. The research results also imply a possibility to develop protein-based vaccines against other Streptococcus infections in animals as well as humans, e.g. tonsillitis.


Story Source:

The above story is based on materials provided by The Swedish Research Council. Note: Materials may be edited for content and length.


Journal Reference:

  1. Guss et al. Getting to Grips with Strangles: An Effective Multi-Component Recombinant Vaccine for the Protection of Horses from Streptococcus equi Infection. PLoS Pathogens, 2009; 5 (9): e1000584 DOI: 10.1371/journal.ppat.1000584

Cite This Page:

The Swedish Research Council. "Good Results For New Vaccine Against Horse Strangles Disease." ScienceDaily. ScienceDaily, 8 October 2009. <www.sciencedaily.com/releases/2009/10/091006135239.htm>.
The Swedish Research Council. (2009, October 8). Good Results For New Vaccine Against Horse Strangles Disease. ScienceDaily. Retrieved February 1, 2015 from www.sciencedaily.com/releases/2009/10/091006135239.htm
The Swedish Research Council. "Good Results For New Vaccine Against Horse Strangles Disease." ScienceDaily. www.sciencedaily.com/releases/2009/10/091006135239.htm (accessed February 1, 2015).

Share This


More From ScienceDaily



More Plants & Animals News

Sunday, February 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nanoscale Sensor Could Help Wine Producers and Clinical Scientists

Nanoscale Sensor Could Help Wine Producers and Clinical Scientists

Reuters - Innovations Video Online (Jan. 30, 2015) A nanosensor that mimics the oral effects and sensations of drinking wine has been developed by Danish and Portuguese researchers. Jim Drury saw it in operation. Video provided by Reuters
Powered by NewsLook.com
Dog-Loving Astronaut Wins Best Photo of 2015

Dog-Loving Astronaut Wins Best Photo of 2015

Buzz60 (Jan. 30, 2015) Retired astronaut and television host, Leland Melvin, snuck his dogs into the NASA studio so they could be in his official photo. As Mara Montalbano (@maramontalbano) shows us, the secret is out. Video provided by Buzz60
Powered by NewsLook.com
U.S. Wants to Analyze DNA from 1 Million People

U.S. Wants to Analyze DNA from 1 Million People

Reuters - US Online Video (Jan. 30, 2015) The U.S. has proposed analyzing genetic information from more than 1 million American volunteers to learn how genetic variants affect health and disease. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Rarest Cat on Planet Caught Attacking Monkeys on Camera

Rarest Cat on Planet Caught Attacking Monkeys on Camera

Buzz60 (Jan. 30, 2015) An African Golden Cat, the rarest large cat on the planet was recently caught on camera by scientists trying to study monkeys. The cat comes out of nowhere to attack those monkeys. Patrick Jones (@Patrick_E_Jones) has the rest. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins