Featured Research

from universities, journals, and other organizations

New Vaccine Strategy May Protect Against Respiratory Syncytial Virus

Date:
January 28, 2010
Source:
American Society for Microbiology
Summary:
A new vaccine strategy inducing antibodies capable of blocking interaction among disease-causing proteins may offer a safe and effective approach against respiratory syncytial virus (RSV).

A new vaccine strategy inducing antibodies capable of blocking interaction among disease-causing proteins may offer a safe and effective approach against respiratory syncytial virus (RSV).

Related Articles


The researchers from the University of Georgia, Athens and the Centers for Disease Control and Prevention, Atlanta, Georgia report their findings in the January 2010 issue of the Journal of Virology.

RSV is a significant human virus that can cause life-threatening respiratory illness in infants, young children, and the elderly. Several prior attempts at RSV vaccine candidates have failed due to lack of protection and greater risk of serious disease. Previous studies have provided strong evidence that G protein peptides can induce protective immunity against RSV, however, CX3C-CX3CR1 G protein interaction may contribute to disease pathogenesis making it an important target for RSV prevention.

In the study researchers studied mice vaccinated with G protein peptides or polypeptides containing the CX3C for antibody production and disease prevention. Results showed that vaccinated mice generated antibodies capable of inhibiting G protein CX3C-CX3CR1 interaction, reducing viral level in the lungs, and minimizing weight loss and pulmonary inflammation.

"The results suggest that RSV vaccines that induce antibodies that block G protein CX3C-CX3CR1 interaction may offer a new, safe, and efficacious RSV vaccine strategy," say the researchers.


Story Source:

The above story is based on materials provided by American Society for Microbiology. Note: Materials may be edited for content and length.


Journal Reference:

  1. W. Zhang, Y. Choi, L.M. Haynes, J.L. Harcourt, L.J. Anderson, L.P. Jones, R.A. Tripp. Vaccination To Induce Antibodies Blocking the CX3C-CX3CR1 Interaction of Respiratory Syncytial Virus G Protein Reduces Pulmonary Inflammation and Virus Replication in Mice. Journal of Virology, 2010; 84 (2): 1148 DOI: 10.1128/JVI.01755-09

Cite This Page:

American Society for Microbiology. "New Vaccine Strategy May Protect Against Respiratory Syncytial Virus." ScienceDaily. ScienceDaily, 28 January 2010. <www.sciencedaily.com/releases/2010/01/100121154239.htm>.
American Society for Microbiology. (2010, January 28). New Vaccine Strategy May Protect Against Respiratory Syncytial Virus. ScienceDaily. Retrieved March 6, 2015 from www.sciencedaily.com/releases/2010/01/100121154239.htm
American Society for Microbiology. "New Vaccine Strategy May Protect Against Respiratory Syncytial Virus." ScienceDaily. www.sciencedaily.com/releases/2010/01/100121154239.htm (accessed March 6, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, March 6, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Just A Half-Hour Of Lost Sleep Could Lead To Weight Gain

Just A Half-Hour Of Lost Sleep Could Lead To Weight Gain

Newsy (Mar. 6, 2015) A new study found losing just half an hour of sleep could make you gain weight. Video provided by Newsy
Powered by NewsLook.com
Suicide Rates Up For Young Women In U.S.

Suicide Rates Up For Young Women In U.S.

Newsy (Mar. 6, 2015) According to a report from the CDC, suicide rates among young women increased from 1994 to 2012 while rates among young men have decreased. Video provided by Newsy
Powered by NewsLook.com
Bupa Eyes India Healthcare Opportunities

Bupa Eyes India Healthcare Opportunities

Reuters - Business Video Online (Mar. 5, 2015) Bupa is hoping to expand in India&apos;s fast-growing health insurance market, once a rule change on foreign investment is implemented. The British private healthcare group&apos;s CEO tells Grace Pascoe why it&apos;s so keen on the new opportunity. Video provided by Reuters
Powered by NewsLook.com
Liberia Releases Last Ebola Patient, But Threat Remains

Liberia Releases Last Ebola Patient, But Threat Remains

Newsy (Mar. 5, 2015) Liberia&apos;s last Ebola patient has been released, and the country hasn&apos;t recorded a new case in a week. However, fears of another outbreak still exist. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins