Featured Research

from universities, journals, and other organizations

Short-term radiation therapy successful on breast cancer

Date:
February 11, 2010
Source:
McMaster University
Summary:
An intense three-week course of radiation therapy is just as effective as the standard five-week regimen for women with early stage breast cancer.

An intense three-week course of radiation therapy is just as effective as the standard five-week regimen for women with early-stage breast cancer.

Dr. Tim Whelan, a professor of oncology of the Michael G. DeGroote School of Medicine at McMaster University, led a team of researchers to find that women who received the accelerated therapy have a low risk of the breast cancer for as long as 12 years after treatment.

The results are to be published in the Feb. 11 issue of the New England Journal of Medicine (NEJM), and have been presented to a meeting of the American Society for Therapeutic Radiology and Oncology.

The study concluded a shorter, more intense course of therapy is as safe and effective as the standard treatment for select women who have undergone breast-conserving surgery.

Women who receive a three-week treatment -- called accelerated hypofractionated whole-breast irradiation -- have a low risk of side effects and recurrence of the cancer more than decade after treatment. It is just as effective as the standard five-week course of radiation following surgery to remove the malignancy.

Dr. Whelan said the study's results will change cancer treatment practice not just in Canada, but throughout North America and around the world.

"This is win-win: shorter intense treatment is better for the patient and less costly to provide," said Dr. Whelan, who is also a radiation oncologist at the Juravinski Cancer Centre at Hamilton Health Sciences.

Many women with early-stage breast cancer are able to undergo breast-conserving therapy to keep their breast after treatment. Typically, this means they first have a lumpectomy to remove the cancer followed by a course of radiation therapy to kill any remaining cancer cells.

Between April 1993 and September 1996, researchers randomly assigned 1,234 women from Ontario and Quebec to be treated with either accelerated radiation or standard radiation. The participants were followed for 12 years to determine if the accelerated whole-breast radiation was as effective as the standard treatment.

A decade after treatment, breast cancer returned in 6.2 percent of patients treated with the accelerated radiation therapy, compared to 6.7 percent for patients treated with standard therapy. Both groups of patients also had a good or excellent cosmetic outcome from the radiation treatments.

Whelan said further research is now looking at even shorter more intensive therapy.

"We're now in the midst of further study on more intense radiation over an even shorter time, and we're seeing positive results."


Story Source:

The above story is based on materials provided by McMaster University. Note: Materials may be edited for content and length.


Cite This Page:

McMaster University. "Short-term radiation therapy successful on breast cancer." ScienceDaily. ScienceDaily, 11 February 2010. <www.sciencedaily.com/releases/2010/02/100210172216.htm>.
McMaster University. (2010, February 11). Short-term radiation therapy successful on breast cancer. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/2010/02/100210172216.htm
McMaster University. "Short-term radiation therapy successful on breast cancer." ScienceDaily. www.sciencedaily.com/releases/2010/02/100210172216.htm (accessed April 20, 2014).

Share This



More Health & Medicine News

Sunday, April 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins