Featured Research

from universities, journals, and other organizations

St. John's wort collection mined for its medicinal value

Date:
April 9, 2010
Source:
USDA/Agricultural Research Service
Summary:
A unique collection of St. John's wort (Hypericum) is providing researchers with genetically diverse, well-documented sources of this herb to use in studies examining its medicinal potential.

ARS maintains a unique collection of genetically diverse St. John's wort to support research into the plant's medicinal potential.
Credit: Norman E. Rees, ARS.

A unique collection of St. John's wort (Hypericum) curated by Agricultural Research Service (ARS) scientists in Ames, Iowa, is providing university collaborators with genetically diverse, well-documented sources of this herb to use in studies examining its medicinal potential.

Related Articles


In collaboration with Mark Widrlechner, a horticulturist with the ARS crop genebank at the North Central Regional Plant Introduction Station in Ames, scientists from the Center for Research on Botanical Dietary Supplements (CRBDS) are screening 180 germplasm accessions of St. John's wort for biologically active compounds. Some may be worth evaluating further in clinical trials for their potential to combat viral infections, reduce inflammation or improve digestive health.

Established in 1948, the ARS Ames crop genebank curates more than 50,000 accessions of ornamental plants, maize, oilseeds, vegetables and other crops, and provides them to researchers for many applications. Accessions with medicinal or nutraceutical value include Echinacea (purple coneflower), Hypericum, Prunella (self-heal) and Actaea racemosa (black cohosh). ARS horticulturist Luping Qu curates the collection and Widrlechner coordinates its use for research at CRBDS, one of six Botanical Research Centers funded by the National Institutes of Health from 2005-2010.

The Hypericum collection at Ames was started in the 1990s and today encompasses about 60 species collected from around the world. This diversity has enabled investigations of genetic, environmental and developmental factors affecting the quantity and quality of bioactive compounds, as well as their modes of action.

Of particular interest is how these compounds interact, and whether those interactions are critical to human health benefits. In a recent issue of Pharmaceutical Biology, researchers noted that combinations of four compounds from St. John's wort (amentoflavone, chlorogenic acid, pseudohypericin and quercetin) were more effective at reducing inflammation in mouse macrophage assays than when each was used alone.

Widrlechner's collaborators include Diane Birt, Kimberly Hammer, Matthew Hillwig, Jingqiang Wei, George Kraus, Patricia Murphy and Eve Wurtele at Iowa State University; Jeffrey Neighbors, David Wiemer, Wendy Maury and Jason Price at the University of Iowa; and Joe-Ann McCoy, formerly with ARS.


Story Source:

The above story is based on materials provided by USDA/Agricultural Research Service. Note: Materials may be edited for content and length.


Cite This Page:

USDA/Agricultural Research Service. "St. John's wort collection mined for its medicinal value." ScienceDaily. ScienceDaily, 9 April 2010. <www.sciencedaily.com/releases/2010/03/100330151945.htm>.
USDA/Agricultural Research Service. (2010, April 9). St. John's wort collection mined for its medicinal value. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/2010/03/100330151945.htm
USDA/Agricultural Research Service. "St. John's wort collection mined for its medicinal value." ScienceDaily. www.sciencedaily.com/releases/2010/03/100330151945.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Plants & Animals News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Arthropod Fossil Might Be Relative Of Spiders, Scorpions

New Arthropod Fossil Might Be Relative Of Spiders, Scorpions

Newsy (Mar. 29, 2015) A 508-million-year-old arthropod that swam in the Cambrian seas is thought to share a common ancestor with spiders and scorpions. Video provided by Newsy
Powered by NewsLook.com
Vietnam Rice Boom Piles Pressure on Farmers and the Environment

Vietnam Rice Boom Piles Pressure on Farmers and the Environment

AFP (Mar. 29, 2015) Vietnam&apos;s drive to become the world&apos;s leading rice exporter is pushing farmers in the fertile Mekong Delta to the brink, say experts, with mounting costs to the environment. Duration: 02:35 Video provided by AFP
Powered by NewsLook.com
Raw: Lioness Has Rare Five-Cub Litter

Raw: Lioness Has Rare Five-Cub Litter

AP (Mar. 27, 2015) A lioness in Pakistan has given birth to five cubs, twice the usual size of a litter. Queen gave birth to two other cubs just nine months ago. (March 27) Video provided by AP
Powered by NewsLook.com
Jockey Motion Tracking Reveals Racing Prowess

Jockey Motion Tracking Reveals Racing Prowess

Reuters - Innovations Video Online (Mar. 26, 2015) Using motion tracking technology, researchers from the Royal Veterinary College (RVC) are trying to establish an optimum horse riding style to train junior jockeys, as well as enhance safety, health and well-being of both racehorses and jockeys. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins