Featured Research

from universities, journals, and other organizations

New microfluidic chip for discriminating bacteria

Date:
September 15, 2010
Source:
American Institute of Physics
Summary:
A new "on-chip" method for sorting and identifying bacteria has been created by biomedical engineers. The discovery may lead to portable devices that could be used for analyzing bacteria-infected blood, finding the causes of urethral irritation, and for screening raw milk and other foods.

A new "on-chip" method for sorting and identifying bacteria has been created by biomedical engineers at Taiwan's National Cheng Kung University. The technique, developed by Hsien-Chang Chang, a professor at the Institute of Biomedical Engineering and the Institute of Nanotechnology and Microsystems Engineering, along with former graduate student I-Fang Cheng and their colleagues, is described in the AIP journal Biomicrofluidics.

Using roughened glass slides patterned with gold electrodes, the researchers created microchannels to sort, trap, and identify bacteria. The technique uses surface enhanced Raman spectroscopy. This type of spectroscopy, says Chang, "is based on the measurement of scattered light from the vibration energy levels of chemical bonds following excitation in a craggy metal surface, which enhances the vibration energy." Different components like proteins or other chemical components on the surface of bacteria become attached to the craggy gold zone; when excited, these components cause representative peaks at different wavelengths, creating spectral "fingerprints."

Although some species of bacteria could show very similar signatures because the components on their surfaces are almost the same, says Chang, bacteria from different genera are distinguishable using the technique.

"In the future, different species of fungi could also be sorted based on their different electrical or physical properties by optimizing conditions such as the flow rate, applied voltage, and frequency," he says. "This portable device could be used for preliminary screening for the pathogenic targets in bacteria-infected blood, urethral irritation, and of raw milk and for food monitoring."


Story Source:

The above story is based on materials provided by American Institute of Physics. Note: Materials may be edited for content and length.


Journal Reference:

  1. I-Fang Cheng, Chi-Chang Lin, Dong-Yi Lin, Hsien-Chang Chang. A dielectrophoretic chip with a roughened metal surface for on-chip surface-enhanced Raman scattering analysis of bacteria. Biomicrofluidics, 2010; 4 (3): 034104 DOI: 10.1063/1.3474638

Cite This Page:

American Institute of Physics. "New microfluidic chip for discriminating bacteria." ScienceDaily. ScienceDaily, 15 September 2010. <www.sciencedaily.com/releases/2010/09/100914095924.htm>.
American Institute of Physics. (2010, September 15). New microfluidic chip for discriminating bacteria. ScienceDaily. Retrieved October 2, 2014 from www.sciencedaily.com/releases/2010/09/100914095924.htm
American Institute of Physics. "New microfluidic chip for discriminating bacteria." ScienceDaily. www.sciencedaily.com/releases/2010/09/100914095924.htm (accessed October 2, 2014).

Share This



More Plants & Animals News

Thursday, October 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Dolphins and Turtles Under Threat in Pakistan

Dolphins and Turtles Under Threat in Pakistan

AFP (Oct. 2, 2014) — The turtles and Dolphins of Pakistan's Indus river - both protected by law - are in a fight for their survival as man's activities threatens their futures. Duration: 02:29 Video provided by AFP
Powered by NewsLook.com
'Harvest Break' Endures in Maine Potato Fields

'Harvest Break' Endures in Maine Potato Fields

AP (Oct. 2, 2014) — Educators and farmers are clinging to a tradition aimed at giving farmers much-needed help in getting potatoes out of the fields and into storage before the ground freezes in the nation's northeast corner. (Oct. 2) Video provided by AP
Powered by NewsLook.com
Attacking Superbugs

Attacking Superbugs

Ivanhoe (Oct. 1, 2014) — Two weapons hospitals can use to attack superbugs. Scientists in Ireland created a new gel resistant to superbugs, and a robot that can disinfect a room in minutes. Video provided by Ivanhoe
Powered by NewsLook.com
Cultural Learning In Wild Chimps Observed For The First Time

Cultural Learning In Wild Chimps Observed For The First Time

Newsy (Oct. 1, 2014) — Cultural transmission — the passing of knowledge from one animal to another — has been caught on camera with chimps teaching other chimps. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins