Featured Research

from universities, journals, and other organizations

Adolescent rats more vulnerable to drug addiction than adults; younger animals consumed more cocaine and worked harder for it than did adults

Date:
November 16, 2010
Source:
Society for Neuroscience
Summary:
Adolescent rats take cocaine more readily than adults, are sensitive to lower doses, and work harder for access to the drug, according to new research. The findings suggest that adolescence is a period of increased vulnerability to drug abuse and addiction.

Adolescent rats take cocaine more readily than adults, are sensitive to lower doses, and work harder for access to the drug, according to new research presented at Neuroscience 2010, the annual meeting of the Society for Neuroscience, held in San Diego. The findings suggest that adolescence is a period of increased vulnerability to drug abuse and addiction.

Related Articles


Earlier use of cocaine is associated with more severe addiction; however, it has been unclear whether this was due to more opportunities for drug exposure or increased sensitivity to addiction in young people.

To answer this question, researchers directed by Michela Marinelli, PhD, at Rosalind Franklin University of Medicine and Science trained adolescent and adult rats to poke their noses into a small hole to obtain cocaine intravenously. Over a wide range of doses, adolescent rats learned how to get cocaine more readily than did the adults, and they also took more cocaine overall. In addition, when the researchers made cocaine harder to get, the adolescent rats worked two to three times harder than the adults to obtain the drug.

"Our study shows, for the first time, that adolescents are more sensitive to lower doses of cocaine, and they will work harder to obtain it," Marinelli said. "Our research is the first to offer scientific evidence that when all opportunities to take drugs are equal, biology alone makes adolescents more likely to use cocaine compared to adults," she said.

Research was supported by the National Institute on Drug Abuse and the American Recovery and Reinvestment Act.


Story Source:

The above story is based on materials provided by Society for Neuroscience. Note: Materials may be edited for content and length.


Cite This Page:

Society for Neuroscience. "Adolescent rats more vulnerable to drug addiction than adults; younger animals consumed more cocaine and worked harder for it than did adults." ScienceDaily. ScienceDaily, 16 November 2010. <www.sciencedaily.com/releases/2010/11/101116104537.htm>.
Society for Neuroscience. (2010, November 16). Adolescent rats more vulnerable to drug addiction than adults; younger animals consumed more cocaine and worked harder for it than did adults. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2010/11/101116104537.htm
Society for Neuroscience. "Adolescent rats more vulnerable to drug addiction than adults; younger animals consumed more cocaine and worked harder for it than did adults." ScienceDaily. www.sciencedaily.com/releases/2010/11/101116104537.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Mind & Brain News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com
Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Milestone Birthdays Can Bring Existential Crisis, Study Says

Milestone Birthdays Can Bring Existential Crisis, Study Says

Newsy (Nov. 21, 2014) Researchers find that as people approach new decades in their lives they make bigger life decisions. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins