Featured Research

from universities, journals, and other organizations

Heavy drinking not linked to common type of gullet cancer, study suggests

Date:
March 14, 2011
Source:
BMJ-British Medical Journal
Summary:
Heavy drinking is not associated with one of the two most common types of gullet (esophageal) cancer, new research suggests.

Heavy drinking is not associated with one of the two most common types of gullet (esophageal) cancer, suggests research published online in Gut.

Gullet cancer is the sixth leading cause of cancer death worldwide and occurs as one of two main types: squamous cell carcinoma or adenocarcinoma.

But while rates of gullet adenocarcinoma have soared in many Western countries over the past three decades, those of squamous cell carcinoma have been falling. The squamous cell variety is strongly linked to alcohol consumption.

The authors pooled data from 11 international studies, involving 15,000 participants and 4,600 cases in the Barrett's Esophagus and Esophageal Adenocarcinoma Consortium (BEACON) on both types of gullet cancer, plus another arising at the junction of the lower gullet and the stomach (oesophagogastric junction or OGJA for short).

Heavy drinkers -- seven or more alcoholic drinks a day -- were more than 9.5 times as likely to develop esophageal squamous cell carcinoma as non-drinkers.

But the authors found no evidence linking this level of alcohol consumption, or, for that matter, any particular type of alcohol, to heightened risk of either esophageal adenocarcinoma or OGJA.

And light drinkers -- half to one unit of alcohol daily -- had a lower risk of these gullet cancers than non-drinkers, although low alcohol consumption could simply reflect other aspects of a healthy lifestyle, or chance, say the authors.

"Our results for [esophageal adenocarcinoma] and OGJA stand in remarkable contrast to results for [esophageal squamous cell carcinoma] in this and previously published studies," comment the authors.

The findings suggest that the risk factors for gullet cancer vary according to the type of disease, they say, adding that other research suggests that weight, smoking, and infection with Helicobacter pylori also confer different levels of risk for the two most common forms of this cancer.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. N. D. Freedman, L. J. Murray, F. Kamangar, C. C. Abnet, M. B. Cook, O. Nyren, W. Ye, A. H. Wu, L. Bernstein, L. M. Brown, M. H. Ward, N. Pandeya, A. C. Green, A. G. Casson, C. Giffen, H. A. Risch, M. D. Gammon, W.-H. Chow, T. L. Vaughan, D. A. Corley, D. C. Whiteman. Alcohol intake and risk of oesophageal adenocarcinoma: a pooled analysis from the BEACON Consortium. Gut, 2011; DOI: 10.1136/gut.2010.233866

Cite This Page:

BMJ-British Medical Journal. "Heavy drinking not linked to common type of gullet cancer, study suggests." ScienceDaily. ScienceDaily, 14 March 2011. <www.sciencedaily.com/releases/2011/03/110314184716.htm>.
BMJ-British Medical Journal. (2011, March 14). Heavy drinking not linked to common type of gullet cancer, study suggests. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2011/03/110314184716.htm
BMJ-British Medical Journal. "Heavy drinking not linked to common type of gullet cancer, study suggests." ScienceDaily. www.sciencedaily.com/releases/2011/03/110314184716.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins