Featured Research

from universities, journals, and other organizations

Developing East Coast fever vaccine

Date:
October 4, 2011
Source:
USDA/Agricultural Research Service
Summary:
A vaccine that protects cattle against East Coast fever, a destructive disease in eastern and central Africa, is being developed.

Scientists from ARS and the International Livestock Research Institute in Nairobi, Kenya, are developing a vaccine for East Coast fever, a major cattle problem in Africa, which may help lead to a vaccine for the related Texas cattle fever.
Credit: USDA

A vaccine that protects cattle against East Coast fever, a destructive disease in eastern and central Africa, is being developed by scientists at the U.S. Department of Agriculture (USDA) and the International Livestock Research Institute (ILRI) in Kenya.

Related Articles


Entomologist Glen Scoles, veterinary medical officer Massaro Ueti and research leader Don Knowles at the Agricultural Research Service (ARS) Animal Disease Research Unit (ADRU) in Pullman, Wash., have been working on the collaborative project for more than five years. ARS is USDA's chief intramural scientific research agency. This research, which looks at combination vaccines for tick-borne diseases, supports USDA's priority of promoting international food security.

Scientists are focusing on the tick that transmits the parasite responsible for East Coast fever, according to Scoles. Because the tick and parasite are similar to the tick and parasite that cause Texas cattle fever in the United States, developing a vaccine for East Coast fever could lead to a vaccine for Texas cattle fever.

In an initial study, scientists developed a polymerase chain reaction (PCR) test that detects parasite DNA in ticks. They used tick populations that were produced at ILRI to have different susceptibilities. Two different strains of ticks- Muguga and Kiambu- were compared. The Muguga ticks had a low level of parasitic infection, whereas the Kiambu ticks were highly susceptible.

Understanding genetic differences between these two tick populations could lead to the identification of proteins that might be good targets for a vaccine to help control East Coast fever, according to Scoles.

The international partnership demonstrates a global community effort to control diseases that limit food and fiber production, according to Knowles. Although East Coast fever isn't currently a problem in the United States, this collaborative research aids in keeping it free of the disease and reducing future risk in other countries. Results of this collaborative research also may be applied to help control other similar parasitic diseases.


Story Source:

The above story is based on materials provided by USDA/Agricultural Research Service. The original article was written by Sandra Avant. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jack D. Sunter, Sonal P. Patel, Robert A. Skilton, Naftaly Githaka, Donald P. Knowles, Glen A. Scoles, Vishvanath Nene, Etienne de Villiers, Richard P. Bishop. A novel SINE family occurs frequently in both genomic DNA and transcribed sequences in ixodid ticks of the arthropod sub-phylum Chelicerata. Gene, 2008; 415 (1-2): 13 DOI: 10.1016/j.gene.2008.01.026

Cite This Page:

USDA/Agricultural Research Service. "Developing East Coast fever vaccine." ScienceDaily. ScienceDaily, 4 October 2011. <www.sciencedaily.com/releases/2011/10/111004162323.htm>.
USDA/Agricultural Research Service. (2011, October 4). Developing East Coast fever vaccine. ScienceDaily. Retrieved December 17, 2014 from www.sciencedaily.com/releases/2011/10/111004162323.htm
USDA/Agricultural Research Service. "Developing East Coast fever vaccine." ScienceDaily. www.sciencedaily.com/releases/2011/10/111004162323.htm (accessed December 17, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Wednesday, December 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
The Hottest Food Trends for 2015

The Hottest Food Trends for 2015

Buzz60 (Dec. 17, 2014) Urbanspoon predicts whicg food trends will dominate the culinary scene in 2015. Mara Montalbano (@maramontalbano) has the story. Video provided by Buzz60
Powered by NewsLook.com
Rover Finds More Clues About Possible Life On Mars

Rover Finds More Clues About Possible Life On Mars

Newsy (Dec. 17, 2014) NASA's Curiosity rover detected methane on Mars and organic compounds on the surface, but it doesn't quite prove there was life ... yet. Video provided by Newsy
Powered by NewsLook.com
Ivory Trade Boom Swamps Law Efforts

Ivory Trade Boom Swamps Law Efforts

Reuters - Business Video Online (Dec. 17, 2014) Demand for ivory has claimed the lives of tens of thousands of African elephants and now a conservation report says the illegal trade is overwhelming efforts to enforce the law. Amy Pollock reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins