Featured Research

from universities, journals, and other organizations

Stinky frogs are a treasure trove of antibiotic substances

Date:
December 8, 2011
Source:
American Chemical Society
Summary:
Some of the nastiest smelling creatures on Earth have skin that produces the greatest known variety of antibacterial substances that hold promise for becoming new weapons in the battle against antibiotic-resistant infections, scientists are reporting. Their research is on amphibians so smelly (like rotten fish, for instance) that scientists term them "odorous frogs."

Some of the nastiest smelling creatures on Earth have skin that produces the greatest known variety of anti-bacterial substances that hold promise for becoming new weapons in the battle against antibiotic-resistant infections.
Credit: Image courtesy of American Chemical Society

Some of the nastiest smelling creatures on Earth have skin that produces the greatest known variety of anti-bacterial substances that hold promise for becoming new weapons in the battle against antibiotic-resistant infections, scientists are reporting. Their research on amphibians so smelly (like rotten fish, for instance) that scientists term them "odorous frogs" appears in ACS' Journal of Proteome Research.

Related Articles


Yun Zhang, Wen-Hui Lee and Xinwang Yang explain that scientists long have recognized frogs' skin as a rich potential source of new antibiotics. Frogs live in warm, wet places where bacteria thrive and have adapted skin that secretes chemicals, known as peptides, to protect themselves from infections. Zhang's group wanted to identify the specific antimicrobial peptides (AMPs), and the most potent to give scientists clues for developing new antibiotics.

They identified more than 700 of these substances from nine species of odorous frogs and concluded that the AMPs account for almost one-third of all AMPs found in the world, the greatest known diversity of these germ-killing chemicals. Interestingly, some of the AMPs have a dual action, killing bacteria directly and also activating the immune system to assist in the battle.

The authors acknowledge funding from the National Basic Research Program of China and The National Natural Science Foundation of China.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Xinwang Yang, Wen-Hui Lee, Yun Zhang. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs. Journal of Proteome Research, 2011; 111118134814004 DOI: 10.1021/pr200782u

Cite This Page:

American Chemical Society. "Stinky frogs are a treasure trove of antibiotic substances." ScienceDaily. ScienceDaily, 8 December 2011. <www.sciencedaily.com/releases/2011/11/111130100449.htm>.
American Chemical Society. (2011, December 8). Stinky frogs are a treasure trove of antibiotic substances. ScienceDaily. Retrieved November 21, 2014 from www.sciencedaily.com/releases/2011/11/111130100449.htm
American Chemical Society. "Stinky frogs are a treasure trove of antibiotic substances." ScienceDaily. www.sciencedaily.com/releases/2011/11/111130100449.htm (accessed November 21, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Friday, November 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Your Complicated Job Might Keep Your Brain Young

Your Complicated Job Might Keep Your Brain Young

Newsy (Nov. 20, 2014) Researchers at the University of Edinburgh found the more complex your job is, the sharper your cognitive skills will likely be as you age. Video provided by Newsy
Powered by NewsLook.com
Mysterious Glow Worms Found in the Amazon

Mysterious Glow Worms Found in the Amazon

Buzz60 (Nov. 20, 2014) Wildlife photographer Jeff Cremer teamed up with entomologist Aaron Pomerantz and others to investigate a predatory glow worm found in the Amazon. Patrick Jones (@Patrick_E_Jones) explains. Video provided by Buzz60
Powered by NewsLook.com
Raw: Huge Snow Covers Buffalo Streets

Raw: Huge Snow Covers Buffalo Streets

AP (Nov. 20, 2014) A new blast of lake-effect snow roared through western New York with thunder and lightning on Thursday, raising to nearly 6 feet the three-day total in parts of the Buffalo area. (Nov. 20) Video provided by AP
Powered by NewsLook.com
Report Warns of Global Chocolate Shortage

Report Warns of Global Chocolate Shortage

Buzz60 (Nov. 20, 2014) A new report warns the world could face a 2.2-billion pound chocolate shortage within the next five years. Mike Janela (@mikejanela) explains. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins