Featured Research

from universities, journals, and other organizations

Producing artificial bones from fish scales

Date:
June 1, 2012
Source:
Tokyo Institute of Technology
Summary:
Scientists have developed technology for producing artificial bones from fish scales and apatite.

Periodic striped patterns at 67nm.
Credit: Copyright : Tokyo Institute of Technology

Tokyo Tech's Toshiyuki Ikoma and Junzo Tanaka have developed technology for producing artificial bones from fish scales and apatite.

Toshiyuki Ikoma and Junzo Tanaka have developed technology for producing artificial bones from fish scales and apatite. "Our technology enables the formation of new bone tissues within three months," says Ikoma. "This is much faster than the six months required using collagen from porcine dermis." The use of fish collagen also mitigates the potential infection of humans with viruses from pigs. "This new material is very safe," emphasizes Ikoma.

Other features of artificial bones fabricated by fish collagen and apatite include the finding that:

(1) the bones have a much higher density and are thereby very strong;

(2) the bones implanted into bone defects transform into bone tissue much faster than those using porcine dermis collagen.

"One of our major aims is to use fish collagen for the treatment of bone tumors in older people whose bones take longer to regenerate," explains Ikoma. "Fish collagen is a material that has the potential of becoming the key material for the development of artificial bones and bone therapy.

In addition to the regeneration of bones from fish collagen, the Tanaka and Ikoma Research group is pursuing projects on nanomedicine and diagnostics. Notably, the Tokyo Institute of Technology group conducts research on tissue engineering and implantable biomaterials in collaboration with medical doctors and biologists. "An interdisciplinary approach with researchers from the medical and engineering fields is very crucial for success" says Ikoma.

In the fish collagen experiments, the researchers have focused on type I collagen extracted from tilapia scales because the scale has little fat and is mainly composed of pure collagen. Intriguingly, Tilapia lives in warm fresh water and the scale collagen shows the highest denaturation (the change of collagen to gelatin) temperature at 36oC, and has no fishy odor.

The Tokyo Tech group has transferred the extraction technology of collagen from tilapia scale to a company. "Interestingly, the structure of collagen fibrils in fish scale is very similar to that of human corneal stroma," says Ikoma. "So the investigation of fish scale will be useful for the reconstruction of corneal stroma."

The unique characteristics of fish collagen show potential for the production of cosmetics. "We have already produced cosmetics including the fish collagen," says Ikoma. "Next, we would like to produce the other products such as cell culture substrates, scaffolds for tissue engineering, and implantable biomaterials."


Story Source:

The above story is based on materials provided by Tokyo Institute of Technology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Zhefeng Xu, Toshiyuki Ikoma, Tomohiko Yoshioka, Motohiro Tagaya, Satoshi Motozuka, Rena Matsumoto, Toshimasa Uemura, Junzo Tanaka. Effect of Glutaraldehyde on Properties of Membranes Prepared from Fish Scale Collagen. MRS Proceedings, 2012; 1418 DOI: 10.1557/opl.2012.396

Cite This Page:

Tokyo Institute of Technology. "Producing artificial bones from fish scales." ScienceDaily. ScienceDaily, 1 June 2012. <www.sciencedaily.com/releases/2012/06/120601093003.htm>.
Tokyo Institute of Technology. (2012, June 1). Producing artificial bones from fish scales. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2012/06/120601093003.htm
Tokyo Institute of Technology. "Producing artificial bones from fish scales." ScienceDaily. www.sciencedaily.com/releases/2012/06/120601093003.htm (accessed July 28, 2014).

Share This




More Plants & Animals News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Raw: Sea Turtle Hatchlings Emerge from Nest

Raw: Sea Turtle Hatchlings Emerge from Nest

AP (July 27, 2014) A live-streaming webcam catches loggerhead sea turtle hatchlings emerging from a nest in the Florida Keys. (July 27) Video provided by AP
Powered by NewsLook.com
Trees Could Save More Than 850 Lives Each Year

Trees Could Save More Than 850 Lives Each Year

Newsy (July 27, 2014) A national study conducted by the USDA Forest Service found that trees collectively save more than 850 lives on an annual basis. Video provided by Newsy
Powered by NewsLook.com
What's To Blame For Worst Ebola Outbreak In History?

What's To Blame For Worst Ebola Outbreak In History?

Newsy (July 27, 2014) A U.S. doctor has tested positive for the deadly Ebola virus, as the worst-ever outbreak continues to grow. Video provided by Newsy
Powered by NewsLook.com
The New York Times Backs Pot Legalization

The New York Times Backs Pot Legalization

Newsy (July 27, 2014) The New York Times has officially endorsed the legalization of marijuana, but why now, and to what end? Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins