Featured Research

from universities, journals, and other organizations

New process to make one-way flu vaccine discovered

Date:
December 18, 2012
Source:
Georgia State University
Summary:
A new process to make a one-time, universal influenza vaccine has been discovered. Researchers found a way to make the one-time vaccine by using recombinant genetic engineering technology that does not use a seasonal virus. Instead, the new vaccine uses a virus' small fragment that does not vary among the different strains of flu viruses.

A new process to make a one-time, universal influenza vaccine has been discovered by a researcher at Georgia State University's Center for Inflammation, Immunity and Infection and his partners.

Associate Professor Sang-Moo Kang and his collaborators have found a way to make the one-time vaccine by using recombinant genetic engineering technology that does not use a seasonal virus.

Instead, the new vaccine uses a virus' small fragment that does not vary among the different strains of flu viruses.

By using the fragment and generating particles mimicking a virus in structure, the immune system can learn to recognize any type of flu virus and attack the pathogen, preventing illness. The research appears in a recent edition of the journal Molecular Therapy, published by the Nature Publishing Group.

"We can now design a vaccine that makes it easier to induce a good immune system response to recognize a pathogen, regardless of how the surface proteins of the virus change," Kang said.

Health officials and scientists must alter flu vaccines every year to match expected strains, and often shortages can result, such as what happened during the 2009 Swine Flu outbreak. A one-time vaccine would prevent such a scenario, Kang said.

"Outbreaks of pandemic can be a dangerous situation, and our current vaccination procedures are not perfect," he said.

Using the new one-time vaccine, using only a fragment rather than the live viral vaccine, such as FluMist, or a killed virus itself, would be safer for people with weakened immune systems, young children and the elderly, Kang said.

The team included researchers from Georgia State, the Emory Vaccine Center at the Emory University School of Medicine, Sungshin Women's University in South Korea and the Animal, Plant and Fisheries Quarantine and Inspection Agency in South Korea.

The research was mainly supported by a grant from the National Institutes of Health and partially supported by the government of South Korea.


Story Source:

The above story is based on materials provided by Georgia State University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Min-Chul Kim, Jae-Min Song, Eunju O, Young-Man Kwon, Youn-Jeong Lee, Richard W Compans, Sang-Moo Kang. Virus-like Particles Containing Multiple M2 Extracellular Domains Confer Improved Cross-protection Against Various Subtypes of Influenza Virus. Molecular Therapy, 2012; DOI: 10.1038/MT.2012.246

Cite This Page:

Georgia State University. "New process to make one-way flu vaccine discovered." ScienceDaily. ScienceDaily, 18 December 2012. <www.sciencedaily.com/releases/2012/12/121218111933.htm>.
Georgia State University. (2012, December 18). New process to make one-way flu vaccine discovered. ScienceDaily. Retrieved September 14, 2014 from www.sciencedaily.com/releases/2012/12/121218111933.htm
Georgia State University. "New process to make one-way flu vaccine discovered." ScienceDaily. www.sciencedaily.com/releases/2012/12/121218111933.htm (accessed September 14, 2014).

Share This



More Plants & Animals News

Sunday, September 14, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Conservationists Face Uphill PR Battle With New Shark Rules

Conservationists Face Uphill PR Battle With New Shark Rules

Newsy (Sep. 14, 2014) — New conservation measures for shark fishing face an uphill PR battle in the fight to slow shark extinction. Video provided by Newsy
Powered by NewsLook.com
Shocker: Journalists Are Utterly Addicted To Coffee

Shocker: Journalists Are Utterly Addicted To Coffee

Newsy (Sep. 13, 2014) — A U.K. survey found that journalists consumed the most amount of coffee, but that's only the tip of the coffee-related statistics iceberg. Video provided by Newsy
Powered by NewsLook.com
'Magic Mushrooms' Could Help Smokers Quit

'Magic Mushrooms' Could Help Smokers Quit

Newsy (Sep. 11, 2014) — In a small study, researchers found that the majority of long-time smokers quit after taking psilocybin pills and undergoing therapy sessions. Video provided by Newsy
Powered by NewsLook.com
Spinosaurus Could Be First Semi-Aquatic Dinosaur

Spinosaurus Could Be First Semi-Aquatic Dinosaur

Newsy (Sep. 11, 2014) — New research has shown that the Spinosaurus, the largest carnivorous dinosaur, might have been just as well suited for life in the water as on land. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

    Technology News



    Save/Print:
    Share:  

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile iPhone Android Web
    Follow Facebook Twitter Google+
    Subscribe RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins