Featured Research

from universities, journals, and other organizations

Sorting stem cells: Scientists propose a new way to isolate early stage embryonic stem cells

Date:
January 3, 2013
Source:
American Institute of Physics (AIP)
Summary:
When an embryonic stem cell is in the first stage of its development it has the potential to grow into any type of cell in the body, a state scientists call undifferentiated. Using an electric field to pull stem cells through a fluid, a team of researchers from Scotland has now demonstrated a way to easily distinguish undifferentiated embryonic stem cells from later-stage stem cells whose fate is sealed.

When an embryonic stem cell is in the first stage of its development it has the potential to grow into any type of cell in the body, a state scientists call undifferentiated. A team of researchers from Scotland has now demonstrated a way to easily distinguish undifferentiated embryonic stem cells from later-stage stem cells whose fate is sealed.

The results are published in the American Institute of Physics' (AIP) journal Biomicrofluidics.

The researchers used an electric field to pull stem cells through a fluid in a process called dielectrophoresis. They varied the frequency of the voltage used to generate the electric field and studied how the cells moved, a response that was affected by the cell's electrical properties. The researchers found that differentiated stem cells could store a significantly greater charge on their outer membranes, a characteristic that might be used to effectively identify and separate them from undifferentiated cells.

The researchers write that the wrinkling, folding, and thinning of a cell's membrane as it differentiates may explain why the later-stage cells can store more charge. The sorting method may prove useful in separating cells for biomedical research or ultimately for treatments of diseases such as Parkinson's.


Story Source:

The above story is based on materials provided by American Institute of Physics (AIP). Note: Materials may be edited for content and length.


Journal Reference:

  1. Srinivas Velugotla, Steve Pells, Heidi K. Mjoseng, Cairnan R. E. Duffy, Stewart Smith, Paul De Sousa, Ronald Pethig. Dielectrophoresis based discrimination of human embryonic stem cells from differentiating derivatives. Biomicrofluidics, 2012; 6 (4): 044113 DOI: 10.1063/1.4771316

Cite This Page:

American Institute of Physics (AIP). "Sorting stem cells: Scientists propose a new way to isolate early stage embryonic stem cells." ScienceDaily. ScienceDaily, 3 January 2013. <www.sciencedaily.com/releases/2013/01/130103130758.htm>.
American Institute of Physics (AIP). (2013, January 3). Sorting stem cells: Scientists propose a new way to isolate early stage embryonic stem cells. ScienceDaily. Retrieved September 1, 2014 from www.sciencedaily.com/releases/2013/01/130103130758.htm
American Institute of Physics (AIP). "Sorting stem cells: Scientists propose a new way to isolate early stage embryonic stem cells." ScienceDaily. www.sciencedaily.com/releases/2013/01/130103130758.htm (accessed September 1, 2014).

Share This




More Health & Medicine News

Monday, September 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Get on Your Bike! London Cycling Popularity Soars Despite Danger

Get on Your Bike! London Cycling Popularity Soars Despite Danger

AFP (Sep. 1, 2014) — Wedged between buses, lorries and cars, cycling in London isn't for the faint hearted. Nevertheless the number of people choosing to bike in the British capital has doubled over the past 15 years. Duration: 02:27 Video provided by AFP
Powered by NewsLook.com
We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) — A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com
Liberia Continues Fight Against Ebola

Liberia Continues Fight Against Ebola

AFP (Aug. 30, 2014) — Authorities in Liberia try to stem the spread of the Ebola epidemic by raising awareness and setting up sanitation units for people to wash their hands. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

Reuters - US Online Video (Aug. 30, 2014) — California lawmakers pass a bill requiring universities to adopt "affirmative consent" language in their definitions of consensual sex, part of a nationwide drive to curb sexual assault on campuses. Linda So reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins