Featured Research

from universities, journals, and other organizations

Leading by the nose: Star-nosed mole reveals how mammals perceive touch, pain

Date:
January 30, 2013
Source:
Public Library of Science
Summary:
The most sensitive patch of mammalian skin known to us isn't human but on the star-shaped tip of the star-nosed mole's snout. Researchers studying this organ have found that the star has a higher proportion of touch-sensitive nerve endings than pain receptors, according to a new study.

Genes expressed in the star-nosed mole's star reveal common mammalian touch and pain sensing molecules.
Credit: Photo by Kenneth Catania, Vanderbilt University / Citation: Kristin A. Gerhold, Maurizio Pellegrino, Makoto Tsunozaki, Takeshi Morita, Duncan B. Leitch, Pamela R. Tsuruda, Rachel B. Brem, Kenneth C. Catania, Diana M. Bautista. The Star-Nosed Mole Reveals Clues to the Molecular Basis of Mammalian Touch. PLoS ONE, 2013; 8 (1): e55001 DOI: 10.1371/journal.pone.0055001

The most sensitive patch of mammalian skin known to us isn't human but on the star-shaped tip of the star-nosed mole's snout. Researchers studying this organ have found that the star has a higher proportion of touch-sensitive nerve endings than pain receptors, according to a study published Jan. 30 in the open access journal PLOS ONE by Diana Bautista and colleagues from the University of California, Berkeley and Vanderbilt University.

Related Articles


Touch and pain are closely intertwined sensations, but very little is known about how these sensations are detected in our cells. In this study, the authors turned to a unique species for answers: the star-nosed mole. In addition to its distinction as the fastest-eating mammal known, the star-nosed mole also possesses one of the most sensitive tactile organs known in the animal kingdom. The star on its nose has the highest density of nerve endings known in any mammalian skin, with over 100,000 fibers in a patch of skin about 1 cm. in diameter. The authors found these nerve endings significantly enriched in neurons sensitive to light touch, with a lower proportion of neurons that detect and respond to pain.

The novel touch and pain receptors they identified in the star-nosed mole were also detected in sensory receptors in mice and humans, suggesting that these receptors are likely to be more common across other mammals as well. According to the authors, their results highlight how examining diverse and highly specialized species can reveal fundamental aspects of biology common across different animals.

Lead author on the study Bautista says, "By studying the star-nosed mole we identified candidate genes that may mediate touch and pain. These genes represent new potential targets for the development of much needed drugs and therapies to treat chronic pain."

The authors are supported by a U.S. National Institutes of Health Innovator Award DOD007123A, the Pew Scholars Program, and the McKnight Scholars Fund (to DMB) and NSF grant 0844743 (to KCC).


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Kristin A. Gerhold, Maurizio Pellegrino, Makoto Tsunozaki, Takeshi Morita, Duncan B. Leitch, Pamela R. Tsuruda, Rachel B. Brem, Kenneth C. Catania, Diana M. Bautista. The Star-Nosed Mole Reveals Clues to the Molecular Basis of Mammalian Touch. PLoS ONE, 2013; 8 (1): e55001 DOI: 10.1371/journal.pone.0055001

Cite This Page:

Public Library of Science. "Leading by the nose: Star-nosed mole reveals how mammals perceive touch, pain." ScienceDaily. ScienceDaily, 30 January 2013. <www.sciencedaily.com/releases/2013/01/130130184156.htm>.
Public Library of Science. (2013, January 30). Leading by the nose: Star-nosed mole reveals how mammals perceive touch, pain. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2013/01/130130184156.htm
Public Library of Science. "Leading by the nose: Star-nosed mole reveals how mammals perceive touch, pain." ScienceDaily. www.sciencedaily.com/releases/2013/01/130130184156.htm (accessed October 24, 2014).

Share This



More Plants & Animals News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Reuters - Innovations Video Online (Oct. 24, 2014) Miniature deep sea animals discovered off the Australian coast almost three decades ago are puzzling scientists, who say the organisms have proved impossible to categorise. Academics at the Natural History of Denmark have appealed to the world scientific community for help, saying that further information on Dendrogramma enigmatica and Dendrogramma discoides could answer key evolutionary questions. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Black Bear Cub Goes Sunday Shopping

Black Bear Cub Goes Sunday Shopping

Reuters - Light News Video Online (Oct. 23, 2014) Price check on honey? Bear cub startles Oregon drugstore shoppers. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Dances With Wolves in China's Wild West

Dances With Wolves in China's Wild West

AFP (Oct. 23, 2014) One man is on a mission to boost the population of wolves in China's violence-wracked far west. The animal - symbol of the Uighur minority there - is under threat with a massive human resettlement program in the region. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins