Featured Research

from universities, journals, and other organizations

Early infant growth rate linked to composition of gut microbiota

Date:
May 9, 2013
Source:
Public Library of Science
Summary:
The composition of gut microbiota in a new-born baby's gut has been linked to the rate of early infant growth. The findings support the assertion that the early development of "microbiota" -- the body's microbial ecosystem -- in an infant can influence growth and thereby the likelihood of obesity.

The composition of gut microbiota in a newborn baby's gut has been linked to the rate of early infant growth.
Credit: © olesiabilkei / Fotolia

The composition of gut microbiota in a newborn baby's gut has been linked to the rate of early infant growth, reports research published this week in PLOS Computational Biology. The findings support the assertion that the early development of "microbiota" -- the body's microbial ecosystem -- in an infant can influence growth and thereby the likelihood of obesity.

The sterile gut of a new-born baby is quickly populated by a variety of different microbes. This study identified connections between different bacteria and both expected and reduced infant growth rates.

The study, set up at the Norwegian Institute of Public Health, by Principal Investigator Merete Eggesbo took data from infants when they were 4, 10, 30 and 120 days old. By looking at faecal samples from 218 babies, the statisticians Richard White and Shyamal Peddada developed a method aimed to identify the points and periods in time where the detection of specific bacterial groups was associated with an infant's development.

Their study showed that the detection of Bacteroides species at day 30 in males was significantly associated with reduced growth. In contrast the presence of E. coli species from four to 30 days after birth was observed to correspond with expected growth in both male and female infants.

The authors mapped part of infant gut microbiota using broad and unspecific probes only, thus the observed associations may be markers for other alterations in the gut microbiota composition. It is also possible that other factors early in life could give rise to such associations and the study may not have been large enough to adequately control for this. However, they believe their method can prove a useful tool for studying this intriguing topic further.

The authors comment: "We have created a new way of looking at the development of gut microbiota over time and relating this development to health outcomes. This is useful to the scientific community as it is difficult to characterise, in a meaningful way, how the gut develops over time. After applying our new method, we found an indication that the composition of early life gut microbiota may be associated with how fast or slow babies grow in early life although there is also the possibility that factors early in life affect both gut microbiota and how fast the baby grows"

Knowledge of how the optimal composition of gut microbiota develops over time is a prerequisite for any successful manipulation of gut microbiota.


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. White RA, Bjørnholt JV, Baird DD, Midtvedt T, Harris JR, et al. Novel Developmental Analyses Identify Longitudinal Patterns of Early Gut Microbiota that Affect Infant Growth. PLoS Comput Biol, 2013 DOI: 10.1371/journal.pcbi.1003042

Cite This Page:

Public Library of Science. "Early infant growth rate linked to composition of gut microbiota." ScienceDaily. ScienceDaily, 9 May 2013. <www.sciencedaily.com/releases/2013/05/130509091213.htm>.
Public Library of Science. (2013, May 9). Early infant growth rate linked to composition of gut microbiota. ScienceDaily. Retrieved September 18, 2014 from www.sciencedaily.com/releases/2013/05/130509091213.htm
Public Library of Science. "Early infant growth rate linked to composition of gut microbiota." ScienceDaily. www.sciencedaily.com/releases/2013/05/130509091213.htm (accessed September 18, 2014).

Share This



More Health & Medicine News

Thursday, September 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Artificial Sweetener Could Promote Diabetes

Artificial Sweetener Could Promote Diabetes

Newsy (Sep. 17, 2014) — Doctors once thought artificial sweeteners lacked the health risks of sugar, but a new study says they can impact blood sugar levels the same way. Video provided by Newsy
Powered by NewsLook.com
Ebola Vaccine Trial Gets Underway at Oxford University

Ebola Vaccine Trial Gets Underway at Oxford University

AFP (Sep. 17, 2014) — A healthy British volunteer is to become the first person to receive a new vaccine for the Ebola virus after US President Barack Obama called for action against the epidemic and warned it was "spiralling out of control." Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) — Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) — President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins