Featured Research

from universities, journals, and other organizations

MERS virus discovered in bat near site of outbreak in Saudi Arabia

Date:
August 21, 2013
Source:
Columbia University's Mailman School of Public Health
Summary:
A 100 percent genetic match for Middle East Respiratory Syndrome has been discovered in an insect-eating bat in close proximity to the first known case of the disease in Saudi Arabia. The discovery points to the likely animal origin for the disease, although researchers say that an intermediary animal is likely also involved.

This is an Egyptian Tomb Bat (Taphozous perforatus) being examined by researchers. One of this type of bat was found to have Middle East Respiratory Syndrome in a study in Saudi Arabia.
Credit: Jonathan H. Epstein/EcoHealth Alliance

A 100% genetic match for Middle East Respiratory Syndrome (MERS) has been discovered in an insect-eating bat in close proximity to the first known case of the disease in Saudi Arabia. The discovery points to the likely animal origin for the disease, although researchers say that an intermediary animal is likely also involved.

Related Articles


Led by team of investigators from the Center for Infection and Immunity (CII) at Columbia University's Mailman School of Public Health, EcoHealth Alliance, and the Ministry of Health of the Kingdom of Saudi Arabia, the study is the first to search for an animal reservoir for MERS in Saudi Arabia, and the first to identify such a reservoir by finding a genetic match in an animal. Results appear online in Emerging Infectious Diseases, a journal of the U.S. Centers for Disease Control and Prevention.

"There have been several reports of finding MERS-like viruses in animals. None were a genetic match. In this case we have a virus in an animal that is identical in sequence to the virus found in the first human case. Importantly, it's coming from the vicinity of that first case," says W. Ian Lipkin, MD, director of the Center for Infection and Immunity and a co-author of the study.

MERS was first described in September 2012 and continues to spread. Close to 100 cases have been reported worldwide, 70 of them from Saudi Arabia. The causative agent, a new type of coronavirus, has been determined; however, the origin of the virus has been unknown until now.

Over a six-week period during field expeditions in October 2012 and April 2013, the researchers collected more than 1,000 samples from seven bat species in regions where cases of MERS were identified in Bisha, Unaizah, and Riyadh. Extensive analysis was performed using polymerase chain reaction and DNA sequencing revealed the presence of a wide range of alpha and beta coronaviruses in up to a third of bat samples. One fecal sample from an Egyptian Tomb Bat (Taphozous perforatus) collected within a few kilometers of the first known MERS victim's home contained sequences of a virus identical to those recovered from the victim.

Bats are the reservoirs of viruses that can cause human disease including rabies, Hendra, Nipah, Marburg, and SARS. In some instances the infection may spread directly from bats to humans through inadvertent inhalation of infected aerosols, ingestion of contaminated food, or, less commonly, a bite wound. In other instances bats can first infect intermediate hosts. The researchers suggest that the indirect method for transmission is more likely in MERS.

"There is no evidence of direct exposure to bats in the majority of human cases of MERS," says Ziad Memish, MD, Deputy Minister of Health, Kingdom of Saudi Arabia, and lead author of the study. "Given that human-to-human transmission is inefficient, we speculate that an as-yet-to-be determined intermediate host plays a critical role in human disease."

"We are continuing to look for evidence of the virus in wildlife and domestic animals, and investigating the mechanisms by which the virus causes human disease," adds Dr. Lipkin. "This is but the first chapter in a powerful collaboration amongst partners committed to global public health."

In the coming days, the group will be reporting the results of its investigation into the possible presence of MERS in camels, sheep, goats, and cattle.


Story Source:

The above story is based on materials provided by Columbia University's Mailman School of Public Health. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ziad A. Memish, Nischay Mishra, Kevin J. Olival, Shamsudeen F. Fagbo, Vishal Kapoor, Jonathan H. Epstein, Rafat AlHakeem, Mushabab Al Asmari, Ariful Islam, Amit Kapoor, Thomas Briese, Peter Daszak, Abdullah A. Al Rabeeah, W. Ian Lipkin. Middle East Respiratory Syndrome Coronavirus in Bats, Saudi Arabia. Emerging Infectious Diseases, 2013; 19 (11) DOI: 10.3201/eid1911.131172

Cite This Page:

Columbia University's Mailman School of Public Health. "MERS virus discovered in bat near site of outbreak in Saudi Arabia." ScienceDaily. ScienceDaily, 21 August 2013. <www.sciencedaily.com/releases/2013/08/130821132714.htm>.
Columbia University's Mailman School of Public Health. (2013, August 21). MERS virus discovered in bat near site of outbreak in Saudi Arabia. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2013/08/130821132714.htm
Columbia University's Mailman School of Public Health. "MERS virus discovered in bat near site of outbreak in Saudi Arabia." ScienceDaily. www.sciencedaily.com/releases/2013/08/130821132714.htm (accessed October 31, 2014).

Share This



More Plants & Animals News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Watch Baby Goose Survive A 400-Foot Cliff Dive

Watch Baby Goose Survive A 400-Foot Cliff Dive

Buzz60 (Oct. 31, 2014) For its nature series Life Story, the BBC profiled the barnacle goose, whose chicks must make a daredevil 400-foot cliff dive from their nests to find food. Jen Markham has the astonishing video. Video provided by Buzz60
Powered by NewsLook.com
World's Salamanders At Risk From Flesh-Eating Fungus

World's Salamanders At Risk From Flesh-Eating Fungus

Newsy (Oct. 31, 2014) The import of salamanders around the globe is thought to be contributing to the spread of a deadly fungus. Video provided by Newsy
Powered by NewsLook.com
Alcoholic Drinks In The E.U. Could Get Calorie Labels

Alcoholic Drinks In The E.U. Could Get Calorie Labels

Newsy (Oct. 31, 2014) A health group in the United Kingdom has called for mandatory calorie labels on alcoholic beverages in the European Union. Video provided by Newsy
Powered by NewsLook.com
Malaria Threat in Liberia as Fight Against Ebola Rages

Malaria Threat in Liberia as Fight Against Ebola Rages

AFP (Oct. 31, 2014) Focus on treating the Ebola epidemic in Liberia means that treatment for malaria, itself a killer, is hard to come by. MSF are now undertaking the mass distribution of antimalarials in Monrovia. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins