Featured Research

from universities, journals, and other organizations

Vitamin C and E supplements may hamper endurance training, study suggests

Date:
February 3, 2014
Source:
Wiley
Summary:
Vitamin C and E supplements may blunt the improvement of muscular endurance -- by disrupting cellular adaptions in exercised muscles, suggests a new study.

Vitamin C and E supplements may blunt the improvement of muscular endurance -- by disrupting cellular adaptions in exercised muscles, suggests a new study published today [3 February] in The Journal of Physiology.

As vitamin C and E supplements are widely used, understanding if they interfere with cellular and physiological adaptations to exercise is of interest to people exercising for health purposes as well as to athletes.

Dr G๘ran Paulsen, who led the study at the Norwegian School of Sport Sciences, explains:

"Our results show that vitamin C and E supplements blunted the endurance training-induced increase of mitochondrial proteins, which are needed to improve muscular endurance."

In the 11-week trial, 54 young, healthy men and women were randomly allocated to receive either 1000mg vitamin C and 235mg vitamin E (consistent with amounts found in shop supplements), or a placebo (a pill containing no active ingredients). Neither the subjects nor the investigators knew which participant received the vitamins or placebos.

The participants completed an endurance training programme, consisting of three to four sessions per week, of primarily running. Fitness tests, blood samples and muscle biopsies were taken before and after the intervention.

Whilst the supplements did not affect maximal oxygen uptake or the results of a 20 metre shuttle test, the results showed that markers for the production of new muscle mitochondria -- the power supply for cells -- increased only in the group without supplements.

The National Health Service (NHS) says taking less than 540mg vitamin E and 1000mg vitamin C supplements per day is unlikely to cause any harm.

Dr Paulsen says:

"Our results indicate that high dosages of vitamin C and E -- as commonly found in supplements -- should be used with caution, especially if you are undertaking endurance training."

A significant trend has been identified, but the molecular processes requires further research.

Dr Paulsen says:

"Future studies are needed to determine the underlying mechanisms of these results, but we assume that the vitamins interfered with cellular signalling and blunted expression of certain genes."

Previous studies show that exercising increases muscle oxidant production, which participates in the signalling processes leading to muscle adaption. It is possible that high doses of vitamins C and E act as antioxidants and take away some of this oxidative stress, hence blocking muscular endurance development.


Story Source:

The above story is based on materials provided by Wiley. Note: Materials may be edited for content and length.


Journal Reference:

  1. Paulsen G, Cumming K, Holden G, Hallen J, Ronnestad B, Sveen O, Skaug A, Paur I, Bastani N, Ostgaard H, Buer C, Midttun M, Freuchen F, Wiig H, Ulseth E, Garthe I, Blomhoff R, Benestad H and Raastad T. Vitamin C and E supplementation hampers cellular adaptation to endurance training in humans: a double-blind randomized control trial. Journal of Physiology, February 2014 DOI: 10.1113/jphysiol.2013.267419

Cite This Page:

Wiley. "Vitamin C and E supplements may hamper endurance training, study suggests." ScienceDaily. ScienceDaily, 3 February 2014. <www.sciencedaily.com/releases/2014/02/140203084022.htm>.
Wiley. (2014, February 3). Vitamin C and E supplements may hamper endurance training, study suggests. ScienceDaily. Retrieved August 21, 2014 from www.sciencedaily.com/releases/2014/02/140203084022.htm
Wiley. "Vitamin C and E supplements may hamper endurance training, study suggests." ScienceDaily. www.sciencedaily.com/releases/2014/02/140203084022.htm (accessed August 21, 2014).

Share This




More Health & Medicine News

Thursday, August 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) — Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
Possible Ebola Patient in Isolation at California Hospital

Possible Ebola Patient in Isolation at California Hospital

Reuters - US Online Video (Aug. 20, 2014) — A patient who may have been exposed to the Ebola virus is in isolation at the Kaiser Permanente South Sacramento Medical Center. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Reasons Why Teen Birth Rates Are At An All-Time Low

Reasons Why Teen Birth Rates Are At An All-Time Low

Newsy (Aug. 20, 2014) — A CDC report says birth rates among teenagers have been declining for decades, reaching a new low in 2013. We look at several popular explanations. Video provided by Newsy
Powered by NewsLook.com
Common Antibiotic Could Lead To Heart-Related Death

Common Antibiotic Could Lead To Heart-Related Death

Newsy (Aug. 20, 2014) — Danish researchers discovered patients taking clarithromycin have an increased risk of dying from a heart-related issue. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins