Featured Research

from universities, journals, and other organizations

Missing link in plant immunity identified

Date:
March 12, 2014
Source:
Norwich BioScience Institutes
Summary:
An enzyme critical to plant immunity has been found to be activated in a previously unknown way, according to new research. The enzyme, the NAPDH oxidase RBOHD, triggers a rapid generation of signalling molecules derived from oxygen that are believed to be detrimental to microbial growth. The newly-discovered way this enzyme is activated, by a protein (called BIK1) fills a gap in how plants perceive a threat and how signals are activated to trigger an immune response.

This is Cyril Zipfel (L) and Yasuhiro Kadota (R) from The Sainsbury Laboratory.
Credit: The Sainsbury Laboratory

After a 30-year search, scientists have uncovered how an enzyme critical to plants' rapid immune response against microbes is activated.

"The insights will open up new ways to improve disease resistance and stress tolerance in plants," says Professor Cyril Zipfel of The Sainsbury Laboratory in Norwich.

The enzyme, the NAPDH oxidase RBOHD, triggers a rapid generation of signalling molecules derived from oxygen that are believed to be detrimental to microbial growth. The newly-discovered way this enzyme is activated, by a protein (called BIK1) fills a gap in how plants perceive a threat and how signals are activated to trigger an immune response.

The work, published in the journal Molecular Cell, was conducted by scientists from The Sainsbury Laboratory and from RIKEN in Yokohama in Japan, whose focus on the interactions between plants and microbes can spark innovation in tackling the world's most important crop diseases.

"Understanding how this enzyme was rapidly activated was an important missing link in our knowledge of plant immunity," says Professor Zipfel.

The scientists revealed that the enzyme is regulated by processes some of which are dependent on calcium and some of which are independent of it.

"Our findings lay the ground for future research investigating how these processes interact and how they switch on and off the molecules essential to defence and stress responses."


Story Source:

The above story is based on materials provided by Norwich BioScience Institutes. Note: Materials may be edited for content and length.


Journal Reference:

  1. Yasuhiro Kadota, Jan Sklenar, Paul Derbyshire, Lena Stransfeld, Shuta Asai, Vardis Ntoukakis, Jonathan DG Jones, Ken Shirasu, Frank Menke, Alexandra Jones, Cyril Zipfel. Direct Regulation of the NADPH Oxidase RBOHD by the PRR-Associated Kinase BIK1 during Plant Immunity. Molecular Cell, March 2014 DOI: 10.1016/j.molcel.2014.02.021

Cite This Page:

Norwich BioScience Institutes. "Missing link in plant immunity identified." ScienceDaily. ScienceDaily, 12 March 2014. <www.sciencedaily.com/releases/2014/03/140312132619.htm>.
Norwich BioScience Institutes. (2014, March 12). Missing link in plant immunity identified. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2014/03/140312132619.htm
Norwich BioScience Institutes. "Missing link in plant immunity identified." ScienceDaily. www.sciencedaily.com/releases/2014/03/140312132619.htm (accessed July 23, 2014).

Share This




More Plants & Animals News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Michigan Plant's Goal: Flower and Die

Michigan Plant's Goal: Flower and Die

AP (July 22, 2014) An 80-year-old agave plant, which is blooming for the first and only time at a University of Michigan conservatory, will die when it's done (July 22) Video provided by AP
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com
CDC Head Concerned About a Post-Antibiotic Era

CDC Head Concerned About a Post-Antibiotic Era

AP (July 22, 2014) Sounding alarms about the growing threat of antibiotic resistance, CDC Director Tom Frieden warned Tuesday if the global community does not confront the problem soon, the world will be living in a devastating post-antibiotic era. (July 22) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins