As nanotechnology makes possible a world of machines too tiny to see, researchers are finding ways to combine living organisms with nonliving machinery to solve a variety of problems.
Like other first-generation bio-robots, the new nanobot engineered at the University of Illinois at Chicago is a far cry from Robocop. It's a robotic germ.
UIC researchers created an electromechanical device -- a humidity sensor -- on a bacterial spore. They call it NERD, for Nano-Electro-Robotic Device. The report is online at Scientific Reports, a Nature open access journal.
"We've taken a spore from a bacteria, and put graphene quantum dots on its surface -- and then attached two electrodes on either side of the spore," said Vikas Berry, UIC associate professor of chemical engineering and principal investigator on the study.
"Then we change the humidity around the spore," he said.
When the humidity drops, the spore shrinks as water is pushed out. As it shrinks, the quantum dots come closer together, increasing their conductivity, as measured by the electrodes.
"We get a very clean response -- a very sharp change the moment we change humidity," Berry said. The response was 10 times faster, he said, than a sensor made with the most advanced human-made water-absorbing polymers.
There was also better sensitivity in extreme low-pressure, low-humidity situations. "We can go all the way down to a vacuum and see a response," said Berry, which is important in applications where humidity must be kept low, for example, to prevent corrosion or food spoilage. "It's also important in space applications, where any change in humidity could signal a leak," he said.
Currently available sensors increase in sensitivity as humidity rises, Berry said. NERD's sensitivity is actually higher at low humidity.
"This is a fascinating device," Berry said. "Here we have a biological entity. We've made the sensor on the surface of these spores, with the spore a very active complement to this device. The biological complement is actually working towards responding to stimuli and providing information."
T. S. Sreeprasad and Phong Nguyen of UIC were lead co-authors on the study. Sreeprasad, a postdoctoral fellow, is now at Rice University in Houston. Ahmed Alshogeathri, Luke Hibbeler, Fabian Martinez and Nolan McNeiland, undergraduate students from Kansas State University, were also co-authors on the paper.
The study was supported by the Terry C. Johnson Center for Basic Cancer Research and partial support from the National Science Foundation (CMMI-1054877, CMMI-0939523 and CMMI-1030963) and the Office of Naval Research (N000141110767).
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