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Overnight fasting may reduce breast cancer risk in women

Date:
April 20, 2015
Source:
University of California, San Diego Health Sciences
Summary:
A decrease in the amount of time spent eating and an increase in overnight fasting reduces glucose levels and may reduce the risk of breast cancer among women, report researchers. Women who fasted for longer periods of time overnight had significantly better control over blood glucose concentrations. The data shows that each three hour increase in nighttime fasting was associated with a 4 percent lower postprandial glucose level, regardless of how much women ate.
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A decrease in the amount of time spent eating and an increase in overnight fasting reduces glucose levels and may reduce the risk of breast cancer among women, report University of California, San Diego School of Medicine researchers in the journal Cancer Epidemiology, Biomarkers & Prevention.

The findings were presented at the American Association of Cancer Research's annual meeting in Philadelphia.

"Increasing the duration of overnight fasting could be a novel strategy to reduce the risk of developing breast cancer," said Catherine Marinac, UC San Diego doctoral candidate and first author on the paper. "This is a simple dietary change that we believe most women can understand and adopt. It may have a big impact on public health without requiring complicated counting of calories or nutrients."

Women who fasted for longer periods of time overnight had significantly better control over blood glucose concentrations. The data shows that each three hour increase in nighttime fasting was associated with a 4 percent lower postprandial glucose level, regardless of how much women ate.

"The dietary advice for cancer prevention usually focuses on limiting consumption of red meat, alcohol and refined grains while increasing plant-based foods," said co-author Ruth Patterson, PhD, UC San Diego Moores Cancer Center associate director for population sciences and program leader of the cancer prevention program. "New evidence suggests that when and how often people eat can also play a role in cancer risk."

Women in the study reported eating five times per day with a mean nighttime fasting of 12 hours. Those who reported longer fast durations also indicated they consumed fewer calories per day, ate fewer calories after 10 p.m. and had fewer eating episodes.

Researchers recommend large-scale clinical trials to confirm that nighttime fasting results in favorable changes to biomarkers of glycemic control and breast cancer risk.


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Materials provided by University of California, San Diego Health Sciences. Note: Content may be edited for style and length.


Journal Reference:

  1. Catherine R. Marinac, Loki Natarajan, Dorothy D. Sears, Linda C. Gallo, Sheri J. Hartman, Elva Arredondo, and Ruth E. Patterson. Prolonged Nightly Fasting and Breast Cancer Risk: Findings from NHANES (2009–2010). Cancer Epidemiology, Biomarkers & Prevention., April 2015 DOI: 10.1158/1055-9965.EPI-14-1292

Cite This Page:

University of California, San Diego Health Sciences. "Overnight fasting may reduce breast cancer risk in women." ScienceDaily. ScienceDaily, 20 April 2015. <www.sciencedaily.com/releases/2015/04/150420084541.htm>.
University of California, San Diego Health Sciences. (2015, April 20). Overnight fasting may reduce breast cancer risk in women. ScienceDaily. Retrieved March 18, 2024 from www.sciencedaily.com/releases/2015/04/150420084541.htm
University of California, San Diego Health Sciences. "Overnight fasting may reduce breast cancer risk in women." ScienceDaily. www.sciencedaily.com/releases/2015/04/150420084541.htm (accessed March 18, 2024).

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