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Longitudinal brain changes during transition from adolescence to adulthood found in ASD

New study about Autism Spectrum Disorder published

Date:
June 11, 2015
Source:
Elsevier
Summary:
The atypical trajectory of cortical/brain development in autism spectrum disorder extends well beyond young childhood and into late adolescence and young adulthood, a new study demonstrates.
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A study published in the June 2015 issue of the Journal of the American Academy of Child and Adolescent Psychiatry demonstrates that the atypical trajectory of cortical/brain development in autism spectrum disorder (ASD) extends well beyond young childhood and into late adolescence and young adulthood.

A considerable amount of work has focused on early structural brain development in ASD utilizing magnetic resonance imaging (MRI). This body of work has revealed evidence for brain overgrowth during the early postnatal years that appears largely absent later in development in ASD. Although several studies of cortical brain structure in adolescence and young adulthood in ASD have been completed, the vast majority has utilized cross-sectional (i.e., one point in time) designs. In one of the first studies to examine longitudinal (i.e., following the same subjects over time) cortical development in ASD during late adolescence and early adulthood, researchers found an exaggeration of the normal thinning of the cortex that occurs during this age range. Moreover, this increased cortical thinning was associated with greater executive function problems (based on behavioral ratings) and ASD social symptoms. This study suggests that the atypical trajectory of cortical/brain development in ASD extends well beyond young childhood and into late adolescence and young adulthood. More work is needed to understand brain development during the transition from adolescence into adulthood and beyond.


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Materials provided by Elsevier. Note: Content may be edited for style and length.


Journal Reference:

  1. Gregory L. Wallace, Ian W. Eisenberg, Briana Robustelli, Nathan Dankner, Lauren Kenworthy, Jay N. Giedd, Alex Martin. Longitudinal Cortical Development During Adolescence and Young Adulthood in Autism Spectrum Disorder: Increased Cortical Thinning but Comparable Surface Area Changes. Journal of the American Academy of Child & Adolescent Psychiatry, 2015; 54 (6): 464 DOI: 10.1016/j.jaac.2015.03.007

Cite This Page:

Elsevier. "Longitudinal brain changes during transition from adolescence to adulthood found in ASD: New study about Autism Spectrum Disorder published." ScienceDaily. ScienceDaily, 11 June 2015. <www.sciencedaily.com/releases/2015/06/150611114406.htm>.
Elsevier. (2015, June 11). Longitudinal brain changes during transition from adolescence to adulthood found in ASD: New study about Autism Spectrum Disorder published. ScienceDaily. Retrieved May 24, 2017 from www.sciencedaily.com/releases/2015/06/150611114406.htm
Elsevier. "Longitudinal brain changes during transition from adolescence to adulthood found in ASD: New study about Autism Spectrum Disorder published." ScienceDaily. www.sciencedaily.com/releases/2015/06/150611114406.htm (accessed May 24, 2017).

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