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E-cigarette use linked to cough reflex sensitivity

Date:
August 20, 2015
Source:
American College of Chest Physicians
Summary:
The popularity of electronic cigarettes has steadily increased worldwide, but little is known about their effects on health. New research suggests that the single use of an electronic cigarette approximating the nicotine exposure of one tobacco cigarette reduces the sensitivity of the cough reflex.
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The popularity of electronic cigarettes has steadily increased worldwide, but little is known about their effects on health. New research suggests that the single use of an electronic cigarette approximating the nicotine exposure of one tobacco cigarette reduces the sensitivity of the cough reflex.

The study tested 30 adult lifetime nonsmokers with no history of asthma or respiratory diseases and used cough tests to determine how e-cigarettes affect the cough reflex. Capsaicin, the pungent extract of red peppers, was used to induce a safe cough in the subjects and establish their baseline cough reflex sensitivity prior to use of electronic cigarette. Each subject then inhaled 30 puffs of an electronic cigarette, which contains nicotine in a vehicle of distilled water. Fifteen minutes after the e-cigarette "vaping" session, subjects were tested again using the capsaicin cough challenge and then tested again after 24 hours. Based on a comparison of results, a significant decrease in cough reflex sensitivity was shown within the subjects as compared with their baseline levels.

The authors found that nicotine is probably responsible for the effect on the cough reflex. Prior research shows that nicotine also promotes cough immediately after ingestion, suggesting that nicotine has a dual action: an immediate stimulation of the cough reflex and a delayed inhibition.


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Materials provided by American College of Chest Physicians. Note: Content may be edited for style and length.


Journal Reference:

  1. Peter V. Dicpinigaitis, Alfredo Lee Chang, Alis J. Dicpinigaitis, Abdissa Negassa. EFFECT OF ELECTRONIC CIGARETTE USE ON COUGH REFLEX SENSITIVITY. CHEST Journal, 2015; DOI: 10.1378/chest.15-0817

Cite This Page:

American College of Chest Physicians. "E-cigarette use linked to cough reflex sensitivity." ScienceDaily. ScienceDaily, 20 August 2015. <www.sciencedaily.com/releases/2015/08/150820134709.htm>.
American College of Chest Physicians. (2015, August 20). E-cigarette use linked to cough reflex sensitivity. ScienceDaily. Retrieved May 28, 2017 from www.sciencedaily.com/releases/2015/08/150820134709.htm
American College of Chest Physicians. "E-cigarette use linked to cough reflex sensitivity." ScienceDaily. www.sciencedaily.com/releases/2015/08/150820134709.htm (accessed May 28, 2017).

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