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Exposure to phthalates could be linked to pregnancy loss

Date:
September 2, 2015
Source:
American Chemical Society (ACS)
Summary:
A new study of more than 300 women suggests that exposure to certain phthalates -- substances commonly used in food packaging, personal-care and other everyday products -- could be associated with miscarriage, mostly between 5 and 13 weeks of pregnancy.
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A new study of more than 300 women suggests that exposure to certain phthalates -- substances commonly used in food packaging, personal-care and other everyday products -- could be associated with miscarriage, mostly between 5 and 13 weeks of pregnancy. The research, appearing in the ACS journal Environmental Science & Technology, is the first epidemiological study on non-work-related exposure to phthalates to provide evidence for the possible link among a general population.

Out of concern over the potential health effects of phthalates, the U.S. has banned six of these substances from use in certain products made for young children. But many are still included as ingredients in paints, medical tubes, vinyl flooring, soaps, shampoos and other items. Research on phthalates has shown that long-term exposure to low levels of the some of these compounds harms lab animals' health and can increase their risk for pregnancy loss. Additionally, at least one study found that female factory workers exposed to high levels of phthalates through their work were at a higher risk for miscarriage. But there is little epidemiological evidence of phthalates' effects on pregnancy among women with non-occupational exposure. Jianying Hu, Huan Shen and colleagues wanted to find out if there might be a link.

The researchers tested urine samples from 132 women who had miscarriages and 172 healthy pregnant women in China. They found pregnancy loss was associated with higher levels of urinary phthalate metabolites from diethyl phthalate (DEP), di-isobutyl phthalate (DiBP) and di-n-butyl phthalate (DnBP). Although this doesn't prove that phthalates cause pregnancy loss, the study suggests an association exists that the researchers say should be studied further.


Story Source:

Materials provided by American Chemical Society (ACS). Note: Content may be edited for style and length.


Journal Reference:

  1. Di Mu, Fumei Gao, Zhanlan Fan, Huan Shen, Hui Peng, Jianying Hu. Levels of Phthalate Metabolites in Urine of Pregnant Women and Risk of Clinical Pregnancy Loss. Environmental Science & Technology, 2015; 49 (17): 10651 DOI: 10.1021/acs.est.5b02617

Cite This Page:

American Chemical Society (ACS). "Exposure to phthalates could be linked to pregnancy loss." ScienceDaily. ScienceDaily, 2 September 2015. <www.sciencedaily.com/releases/2015/09/150902102649.htm>.
American Chemical Society (ACS). (2015, September 2). Exposure to phthalates could be linked to pregnancy loss. ScienceDaily. Retrieved May 23, 2017 from www.sciencedaily.com/releases/2015/09/150902102649.htm
American Chemical Society (ACS). "Exposure to phthalates could be linked to pregnancy loss." ScienceDaily. www.sciencedaily.com/releases/2015/09/150902102649.htm (accessed May 23, 2017).

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