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If you make impulsive choices you should blame your parents: It's genetic

Date:
December 8, 2015
Source:
American College of Neuropsychopharmacology
Summary:
'Delay discounting' is the tendency to take a smaller reward now rather than waiting for a larger one available later. According to a report, delay discounting is strongly influenced by genetics. Studying 602 twins, researchers found that genes accounted for about half of the individual differences in this trait, which can profoundly affect daily life and psychiatric well-being.
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'Delay discounting' is the tendency, given the choice, to take a smaller reward that is available immediately, instead of a larger reward that will be delivered in the future. According to a report presented at the American College of Neuropsychopharmacology annual meeting in Hollywood, Florida, delay discounting is strongly influenced by our genetic makeup. That is, it is a trait that can be inherited. Identifying the 'delay discounting' genes, and the proteins they code for, will be important for understanding the basis of a variety of psychiatric disorders, especially addictions and other disorders that involve impulsive decision-making.

In a study of 602 twins, Dr. Andrey Anokhin and his colleagues at Washington University School of Medicine found that delay discounting gradually improves as teens get older, such that 18 year-olds have a greater ability or tendency to wait for the larger delayed reward, as compared to younger teens. Apart from age, genes accounted for about half of the difference among individuals in their level of delay discounting. Many genes are likely to influence delay discounting; and some of Dr. Ahokhin's preliminary data suggest that these 'impulsivity genes' may include genes coding for enzymes that synthesize the neurotransmitter serotonin and receptors where serotonin binds in the brain.

While it is tantalizing to speculate that the associations between delay discounting and serotonin-related genes may ultimately point the way to new treatments for addictions and other disorders involving impulsive choice, Dr. Anokhin cautions that "it is very early to link this speculation to a clinical application."

Ongoing studies by investigators across the country, including Drs. Abraham Palmer and James MacKillop, who also participated in the conference, involve analysis of DNA and questionnaire responses from as many as 25,000 human subjects in order to identify specific genes involved in delay discounting. These studies offer to further our understanding of a behavioral trait that can have profound effects on daily life and psychiatric well-being.


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American College of Neuropsychopharmacology. "If you make impulsive choices you should blame your parents: It's genetic." ScienceDaily. ScienceDaily, 8 December 2015. <www.sciencedaily.com/releases/2015/12/151208081342.htm>.
American College of Neuropsychopharmacology. (2015, December 8). If you make impulsive choices you should blame your parents: It's genetic. ScienceDaily. Retrieved May 23, 2017 from www.sciencedaily.com/releases/2015/12/151208081342.htm
American College of Neuropsychopharmacology. "If you make impulsive choices you should blame your parents: It's genetic." ScienceDaily. www.sciencedaily.com/releases/2015/12/151208081342.htm (accessed May 23, 2017).

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