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Gene variation in athletes might signify longer recovery following concussion

Date:
March 5, 2016
Source:
American Orthopaedic Society for Sports Medicine
Summary:
Genetic research on concussions is progressing in many different avenues. However, researchers believe there may be a new genetic connection regarding recovery rates following a sports-related concussion.
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Genetic research on concussions is progressing in many different avenues. However, researchers presenting their work at the American Orthopaedic Society for Sports Medicine's (AOSSM) Specialty Day, believe there may be a new genetic connection regarding recovery rates following a sports-related concussion.

"Athletes carrying a specific genotype (CACNA1E rs704326) in our study were found to have a much greater risk of a prolonged recovery following concussion," said lead author, Jane McDevitt, PhD from Temple University in Philadelphia. "Athletes who also reported having balance issues/deficits were also more likely to take a longer time to recover."

McDevitt and her team analyzed information from 40 athletes with a diagnosed concussion from a hospital concussion program. Researchers further evaluated the concussion injury characteristics, acute signs, symptoms and then objective screenings, such as vestibular ocular assessments, balance error scoring, and Immediate Post-Concussion Assessment and Cognitive Testing exam. In addition, study participants provided a salivary sample to isolate certain DNA.

"We need to perform additional research but we think there may be a connection between the genetic proteins and the increase of calcium which leads to the deficits in recovery," said McDevitt.


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Materials provided by American Orthopaedic Society for Sports Medicine. Note: Content may be edited for style and length.


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American Orthopaedic Society for Sports Medicine. "Gene variation in athletes might signify longer recovery following concussion." ScienceDaily. ScienceDaily, 5 March 2016. <www.sciencedaily.com/releases/2016/03/160305111835.htm>.
American Orthopaedic Society for Sports Medicine. (2016, March 5). Gene variation in athletes might signify longer recovery following concussion. ScienceDaily. Retrieved May 28, 2017 from www.sciencedaily.com/releases/2016/03/160305111835.htm
American Orthopaedic Society for Sports Medicine. "Gene variation in athletes might signify longer recovery following concussion." ScienceDaily. www.sciencedaily.com/releases/2016/03/160305111835.htm (accessed May 28, 2017).

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