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Stem cells from umbilical cord blood may help treat eczema

Date:
June 7, 2016
Source:
Wiley
Summary:
A new study suggests that treatment with stem cells from umbilical cord blood might be an effective therapy for patients with moderate-to-severe eczema, or atopic dermatitis. For the clinical trial, 34 patients were randomly assigned to receive a low dose or high dose of the cells subcutaneously. Fifty five percent of patients who received the high dose showed a 50% reduction in what’s known as the Eczema Area and Severity Index score at week 12.
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A new study suggests that treatment with stem cells from umbilical cord blood might be an effective therapy for patients with moderate-to-severe eczema, or atopic dermatitis.

For the clinical trial, 34 patients were randomly assigned to receive a low dose or high dose of the cells subcutaneously.

Fifty five percent of patients who received the high dose showed a 50% reduction in what's known as the Eczema Area and Severity Index score at week 12. Immune-related markers of atopic dermatitis also decreased significantly.

"This study is a first-in-class study demonstrating that adults with moderate-to-severe atopic dermatitis responded to a treatment of stem cells derived from umbilical cord blood," said Dr. Tae-Yoon Kim, senior author of the Stem Cells study. "The single treatment of stem cells in patients resulted in the significant and persistent improvement in disease symptoms throughout the follow-up period of 12 weeks."

The study was conducted at Seoul St. Mary's Hospital in collaboration with Seoul National University (with co-senior author, Dr. Kyung-Sun Kang).


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Materials provided by Wiley. Note: Content may be edited for style and length.


Journal Reference:

  1. Hyung-Sik Kim, Ji Hyun Lee, Kyoung-Hwan Roh, Hee Jin Jun, Kyung-Sun Kang, Tae-Yoon Kim. Clinical Trial of Human Umbilical Cord Blood-derived Stem Cells for the Treatment of Moderate-to-Severe Atopic Dermatitis: Phase I/IIa Studies. STEM CELLS, 2016; DOI: 10.1002/stem.2401

Cite This Page:

Wiley. "Stem cells from umbilical cord blood may help treat eczema." ScienceDaily. ScienceDaily, 7 June 2016. <www.sciencedaily.com/releases/2016/06/160607080935.htm>.
Wiley. (2016, June 7). Stem cells from umbilical cord blood may help treat eczema. ScienceDaily. Retrieved May 28, 2017 from www.sciencedaily.com/releases/2016/06/160607080935.htm
Wiley. "Stem cells from umbilical cord blood may help treat eczema." ScienceDaily. www.sciencedaily.com/releases/2016/06/160607080935.htm (accessed May 28, 2017).

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