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Is bone strength hereditary?

Date:
July 19, 2017
Source:
Wiley
Summary:
A new study indicates that bone strength may be inherited and that its genetic determinants are to some extent shared with bone mineral density.
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A new study indicates that bone strength may be inherited and that its genetic determinants are to some extent shared with bone mineral density.

The findings may be used to help inform other studies seeking to identify specific genetic variants underlying susceptibility to fractures. Knowledge of molecular mechanisms underlying bone strength is important for predicting individuals' fracture risk and for developing effective prevention and treatment strategies.

"Having high resolution three-dimensional images allowed us to estimate the strength of the bone, called failure load, using a technique called micro-finite element analysis," said Dr. Douglas Kiel, senior author of the Journal of Bone and Mineral Research study. "We were able to then determine that actual bone strength is an inherited measurement. Future genetic studies of bone can use this measure to learn about genes that are important to skeletal health."


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Journal Reference:

  1. Dennis M Black, Jane A Cauley, Rachel Wagman, Kristine Ensrud, Howard A Fink, Teresa A Hillier, Li-Yung Lui, Steven R Cummings, John T Schousboe, Nicola Napoli. The Ability of a Single BMD and Fracture History Assessment to Predict Fracture Over 25 Years in Postmenopausal Women: The Study of Osteoporotic Fractures. Journal of Bone and Mineral Research, 2017; DOI: 10.1002/jbmr.3194

Cite This Page:

Wiley. "Is bone strength hereditary?." ScienceDaily. ScienceDaily, 19 July 2017. <www.sciencedaily.com/releases/2017/07/170719100531.htm>.
Wiley. (2017, July 19). Is bone strength hereditary?. ScienceDaily. Retrieved October 6, 2024 from www.sciencedaily.com/releases/2017/07/170719100531.htm
Wiley. "Is bone strength hereditary?." ScienceDaily. www.sciencedaily.com/releases/2017/07/170719100531.htm (accessed October 6, 2024).

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